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Stimulated cortisol secretion is not correlated with prednisone dose or with steroid side-effects in children after renal transplantation.

Author: HellingerA, KlausG, RevermannT, SoergelM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the potential association between adrenocortical function and the development of side effects in pediatric patients receiving triple immunosuppression after renal transplantation. The researchers hypothesized that assessing adrenal function through ACTH stimulation could predict the development of side effects.
Paper Details　
Original Abstract of the Article :
Impairment of adrenocortical function and other adverse effects have to be considered whenever corticosteroids are applied for a prolonged period of time. We hypothesized that the assessment of adrenal function with adrenocortiocotropin (ACTH) stimulation reflects the sensitivity to corticosteroids ...See full text at original site
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引用元：
https://doi.org/10.1034/j.1399-3046.2002.01092.x

データ提供：米国国立医学図書館（NLM）

Cortisol Levels and Steroid Side Effects: A Desert Oasis of Understanding

This research ventures into the intriguing world of steroid use after kidney transplantation, an important topic for those navigating the desert of recovery. This study explored the relationship between cortisol levels and steroid side effects in children undergoing triple immunosuppression after renal transplantation.

Cortisol Levels and Steroid Side Effects: A Desert Oasis of Understanding

The researchers discovered that cortisol levels, a key hormone in the body, are not directly correlated with prednisone dosage or the development of side effects in these children. This finding is like navigating a desert with a trusty compass; it helps to understand the complex interplay between steroid use and the body's natural responses.

Managing Steroid Side Effects in Children

This study suggests that simply measuring cortisol levels might not be a reliable indicator of steroid side effects in children after renal transplantation. The desert of recovery is filled with complexities, and understanding the delicate balance between steroid use and the body's natural processes is crucial.

Dr.Camel's Conclusion

This study underscores the importance of understanding the complexities of steroid use and its impact on the body. It’s like studying the intricate patterns of sand dunes in a desert, gaining a deeper understanding of the landscape. Further research is necessary to determine other reliable indicators of steroid side effects in this population.
Date :
  1. Date Completed 2003-01-07
  2. Date Revised 2019-11-06
Further Info :

Pubmed ID

12234268

DOI: Digital Object Identifier

10.1034/j.1399-3046.2002.01092.x

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Article Analysis
・Side Effects of prednisone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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