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Randomized adjuvant trial of tamoxifen and goserelin versus cyclophosphamide, methotrexate, and fluorouracil: evidence for the superiority of treatment with endocrine blockade in premenopausal patients with hormone-responsive breast cancer--Austrian Breast and Colorectal Cancer Study Group Trial 5.
Author: , BauernhoferThomas, FridrikMichael, GnantMichael, HaiderKarin, HausmaningerHubert, JakeszRaimund, KubistaErnst, KwasnyWerner, MenzelChristian, MlineritschBrigitte, SamoniggHellmut, SeifertMichael, StegerGuenther, SteindorferPeter, WetteViktor
Original Abstract of the Article :
Effective adjuvant treatment modalities in premenopausal breast cancer patients today include chemotherapy, ovariectomy, and tamoxifen administration. The purpose of Austrian Breast and Colorectal Cancer Study Group Trial 5 was to compare the efficacy of a combination endocrine treatment with standa...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1200/JCO.2002.09.112
データ提供:米国国立医学図書館(NLM)
Endocrine Blockade vs. Chemotherapy in Premenopausal Breast Cancer
Breast cancer is a formidable foe, affecting countless women worldwide. It's like a fierce desert beast, threatening their health and well-being. This study compares the efficacy of endocrine blockade, a treatment that blocks the production of hormones that fuel breast cancer growth, with standard chemotherapy in premenopausal women with hormone-responsive breast cancer. The researchers aimed to determine which treatment approach was more effective, a quest like finding the most effective weapon to fight the desert beast.
Endocrine Blockade: A Superior Adjuvant Treatment
The study found that endocrine blockade, using a combination of tamoxifen and goserelin, was superior to standard chemotherapy in terms of preventing cancer recurrence. This is like wielding a powerful antitoxin against the desert beast, effectively neutralizing its threat. The study suggests that endocrine blockade should be considered a primary treatment option for premenopausal women with hormone-responsive breast cancer.
Improving Outcomes for Breast Cancer Patients
The study's findings have significant implications for the treatment of breast cancer, offering a new approach to preventing recurrence and improving outcomes for premenopausal women. It's like discovering a new oasis in the desert of breast cancer treatment, providing a more effective and less toxic approach to combat this disease.
Dr.Camel's Conclusion
This study is a testament to the ongoing advancements in breast cancer treatment, a journey like a caravan traversing a vast desert, seeking a cure for this devastating disease. By exploring new treatment approaches like endocrine blockade, we can equip ourselves with powerful tools to combat breast cancer and offer hope to those affected by this disease.
Date :
- Date Completed 2003-01-15
- Date Revised 2016-11-02
Further Info :
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