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Borderline personality disorder in major depression: symptomatology, temperament, character, differential drug response, and 6-month outcome.

Author: CloningerRobert C, JoycePeter R, LutySuzanne E, McKenzieJanice M, MulderRoger T, SullivanPatrick F

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the impact of personality disorders on the treatment of depression. The results showed that patients with borderline personality disorder (BPD) had a poorer short-term response to nortriptyline compared to fluoxetine, but had favorable long-term outcomes in terms of depressive symptoms and social adjustment.
Paper Details　
Original Abstract of the Article :
Among 183 depressed patients participating in a randomized long-term treatment trial of fluoxetine and nortriptyline, 30 patients had borderline personality disorder (BPD), 53 had other personality disorders (OPD), and 100 had no personality disorders (NPD). The borderline depressed patients had ear...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12524634

データ提供：米国国立医学図書館（NLM）

Borderline Personality Disorder and Major Depression: A Complex Journey

Depression can be a challenging journey, and when it's intertwined with borderline personality disorder (BPD), the path can become even more complex. This study explores the unique characteristics of depression in individuals with BPD, examining their symptomatology, temperament, and treatment outcomes. It's like navigating a desert with a complex landscape, requiring a deeper understanding of the terrain to find the right path to recovery.

Navigating the Terrain of Depression and BPD

The study revealed that individuals with BPD experiencing depression tend to have a more chronic course, with earlier onset and a higher risk of suicide attempts and self-harm. This underscores the need for tailored treatment approaches to address the unique challenges faced by this population. It's like recognizing the distinct features of a desert landscape, guiding our approach to finding a safe and effective path.

Finding Effective Treatment for Depression and BPD

This research highlights the crucial need for individualized treatment approaches for individuals with BPD experiencing depression. By understanding the unique characteristics of this population, clinicians can develop effective strategies to guide them towards recovery. It's like having a skilled guide who understands the intricacies of the desert, leading individuals through the challenges and towards a brighter future.

Dr. Camel's Conclusion

This study sheds light on the complex interplay between BPD and major depression, emphasizing the need for tailored treatment approaches to address the unique challenges faced by this population. By understanding the distinct characteristics of this group, clinicians can provide more effective care, guiding individuals towards recovery and a more fulfilling life.

Date :
  1. Date Completed 2003-04-22
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

12524634

DOI: Digital Object Identifier

S0010440X0300021X

Related Literature

Article Analysis
・Effective treatment of personality disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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