Acute migraine treatment with droperidol: A randomized, double-blind, placebo-controlled trial.

Author: AlamA S, MendizabalJ E, RothrockJ F, SilbersteinS D, YoungW B

Paper Details 
Original Abstract of the Article :
BACKGROUND: The treatment of a migraine attack can be difficult when first-line medication is unsuccessful and options for parenteral "rescue" therapy are limited. METHODS: A randomized, double-blind, placebo-controlled, dose-ranging, multicenter study was conducted to assess the efficacy and toler...See full text at original site
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引用元:
https://doi.org/10.1212/01.wnl.0000042477.63516.b2

データ提供:米国国立医学図書館(NLM)

Migraine: Finding Relief in the Desert of Pain

Migraines are a debilitating condition that can cause intense pain and disrupt daily life. This research focuses on the acute treatment of migraines, exploring the efficacy of droperidol, a medication typically used for nausea and vomiting.

The authors conducted a randomized, double-blind, placebo-controlled trial to assess the effectiveness of droperidol for migraine headache. They found that droperidol was significantly more effective than placebo in reducing headache pain and associated symptoms, such as nausea, vomiting, photophobia, and phonophobia. However, they also observed that droperidol was associated with adverse effects, particularly anxiety, akathisia, and somnolence.

Droperidol: A Potential Alternative for Migraine Relief

This research suggests that droperidol may be a viable treatment option for patients with migraine headaches who do not respond well to first-line medications. The study highlights the potential of droperidol as a 'rescue therapy' for acute migraine attacks, providing relief when other medications fail. However, the authors emphasize the need for careful monitoring to manage potential adverse effects.

Managing Migraine Pain

Migraine is a challenging condition, but various treatment options exist. This research provides valuable insights into the potential of droperidol as a rescue therapy for acute migraine attacks. It's important to discuss the potential risks and benefits of this medication with your doctor to determine the best approach for managing your migraines.

Dr. Camel's Conclusion

The desert of migraine pain can be a relentless and isolating experience. This research offers a glimmer of hope by exploring the potential of droperidol as a rescue therapy for those struggling to find relief. While droperidol has shown promise, it is essential to weigh the potential benefits against the risks and to work closely with your doctor to develop a personalized treatment plan.

Date :
  1. Date Completed 2003-02-05
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

12552051

DOI: Digital Object Identifier

10.1212/01.wnl.0000042477.63516.b2

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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