The addition of droperidol or clonidine to epidural tramadol shortens onset time and increases duration of postoperative analgesia.

Author: BalciCanan, GönüllüMustafa, GürsesErcan, SungurtekinHülya, TomatirErkan

Paper Details 
Original Abstract of the Article :
PURPOSE: To compare tramadol alone and the combinations of either tramadol-clonidine or tramadol-droperidol with regard to analgesic and adverse effects. METHODS: After Ethic's Committee approval and patient informed consent were obtained, epidural catheters were inserted preoperatively at the L(3-...See full text at original site
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引用元:
https://doi.org/10.1007/BF03017847

データ提供:米国国立医学図書館(NLM)

Adding Droperidol or Clonidine to Epidural Tramadol: A Quest for Enhanced Postoperative Analgesia

The world of pain management is a constant dance between minimizing discomfort and maximizing patient well-being. This study explores a particularly fascinating approach to managing pain after surgery: epidural analgesia. Epidural analgesia, a technique that involves delivering pain-relieving medications directly to the spinal cord, is like providing a soothing oasis in the middle of a scorching desert. The authors investigated the effectiveness of combining tramadol, a commonly used pain reliever, with either droperidol or clonidine to achieve prolonged pain relief in patients undergoing lower abdominal surgery.

The results of this research highlight the potential benefits of combining tramadol with droperidol or clonidine. The study found that adding either of these medications to the epidural tramadol significantly prolonged pain relief compared to using tramadol alone. This finding suggests that these combinations might be valuable tools in the postoperative pain management toolbox.

A Balancing Act: Analgesia and Side Effects

While the study revealed the potential for improved pain relief, it also highlighted the importance of considering side effects. While both combinations showed benefits, the study revealed that clonidine was associated with increased sedation and decreased blood pressure and heart rate. Droperidol, however, was found to be a more favorable option due to its lack of significant side effects, with the exception of nausea.

Managing Pain Without Compromising Safety

This research underscores the importance of a careful balance between effective pain management and safety. The study's findings provide valuable insights for clinicians seeking to optimize postoperative pain control while minimizing the risk of unwanted side effects.

Dr. Camel's Conclusion

This study emphasizes the need for a thoughtful approach to pain management, especially in the postoperative setting. The combination of tramadol with either droperidol or clonidine shows promise for enhancing postoperative pain relief, but clinicians must consider the potential side effects. It's like navigating a sandstorm - you need to balance your options carefully to achieve the best possible outcome.

Date :
  1. Date Completed 2003-05-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12560305

DOI: Digital Object Identifier

10.1007/BF03017847

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English

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