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Steroid and antihistamines modulate RANTES release in cultured peripheral blood mononuclear cells of atopic patients.
Author: CarusoR., CavallucciE., Di GioacchinoM., Di IorioA., GranaM., PaganelliR., PaoliniF., RamondoS., RealeM., SchiavoneC., TheoharidesT. C., VernaN.
Original Abstract of the Article :
RANTES plays a crucial role in cell recruitment in allergic inflammation. We investigated the pharmacological modulation of RANTES release in cultured peripheral blood mononuclear cells obtained from allergic patients with active asthma. Chemokine production was assessed before and after 15 day trea...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/039463200201500104
データ提供:米国国立医学図書館(NLM)
Modulating RANTES Release: Navigating the Sands of Allergic Inflammation
Allergic inflammation, a common and often troublesome condition, is characterized by the recruitment of immune cells to the site of allergic reaction. This study investigates the pharmacological modulation of RANTES release, a key chemokine involved in allergic inflammation, in cultured peripheral blood mononuclear cells from atopic patients. The study's findings provide valuable insights into the potential of corticosteroids and antihistamines in controlling allergic inflammation.
Corticosteroids and Antihistamines: Tools for Managing Allergic Inflammation
The study demonstrates that both corticosteroids and antihistamines can effectively reduce RANTES release in cultured peripheral blood mononuclear cells. These findings suggest that these medications may play a role in managing allergic inflammation by reducing the recruitment of immune cells to the site of allergic reaction. Like a desert traveler seeking a safe passage, these medications can help to navigate the treacherous terrain of allergic inflammation.
Navigating the Desert of Allergic Reactions
This research highlights the importance of understanding the complex mechanisms underlying allergic inflammation and developing effective strategies for managing this common condition. Like a desert navigator, healthcare providers must carefully consider the individual needs of each patient and select the most appropriate treatment approach to minimize the impact of allergic reactions.
Dr. Camel's Conclusion
This study provides valuable insights into the potential of corticosteroids and antihistamines in managing allergic inflammation. These medications, like a desert oasis, can offer relief from the symptoms of allergic reactions and help to control the inflammatory response. However, like a desert mirage, further research is needed to fully understand the long-term effects of these medications and optimize their use in clinical practice.
Date :
- Date Completed n.d.
- Date Revised 2019-11-20
Further Info :
Related Literature
English
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