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Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma.

Author: Baena-CagnaniCarlos E, BergerWilliam E, DanzigMelvyn, DuBuskeLawrence M, GurnéSandra E, LorberRichard, StryszakPaul

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Desloratadine and montelukast were both effective in improving asthma symptoms and reducing beta(2)-agonist use in patients with concomitant seasonal allergic rhinitis (SAR) and asthma.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Asthma and seasonal allergic rhinitis (SAR) are recognized as manifestations of a single airway disease. Desloratadine has demonstrated efficacy in treating SAR symptoms, including nasal obstruction. METHODS: Safety and efficacy of desloratadine and montelukast each were assessed in a d...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12740532

データ提供：米国国立医学図書館（NLM）

Desloratadine vs. Montelukast for Asthma and Allergic Rhinitis

The world of asthma and allergic rhinitis can be a vast and unpredictable desert, with symptoms that ebb and flow like shifting sand dunes. This study explored the effectiveness of two common treatments, desloratadine and montelukast, for patients experiencing both asthma and seasonal allergic rhinitis (SAR). It aimed to compare the efficacy of these medications in alleviating asthma symptoms and reducing the need for rescue medications like beta2-agonists. The study included patients with SAR and asthma symptoms, randomly assigned to receive either desloratadine, montelukast, or a placebo. The researchers assessed changes in asthma symptom severity, lung function, and beta2-agonist usage over a four-week period.

Finding Relief in the Asthma Desert: Desloratadine and Montelukast

This study revealed that both desloratadine and montelukast effectively reduced asthma symptoms and the need for beta2-agonists in patients with SAR and asthma. The study found that both treatments were comparable in their effectiveness, suggesting that they could be viable options for managing this combined condition.

Navigating the Desert: Choosing the Right Treatment

This research highlights the potential of both desloratadine and montelukast as effective treatments for managing the combined symptoms of asthma and seasonal allergic rhinitis. It emphasizes the importance of personalized medicine, considering individual patient characteristics and preferences when choosing the most appropriate treatment approach.

Dr.Camel's Conclusion

This study is like finding a cool oasis in the desert of asthma and allergic rhinitis. It demonstrates that both desloratadine and montelukast can effectively alleviate symptoms and improve quality of life for patients with this combined condition. This research underscores the importance of personalized medicine and finding the right treatment approach to navigate the sometimes challenging journey of managing asthma and allergic rhinitis.

Date :
  1. Date Completed 2003-06-17
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

12740532

DOI: Digital Object Identifier

70218

Related Literature

Article Analysis
・Effects of desloratadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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