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Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposure.

Author: HarrisA G, HorakF, StübnerP, ZieglmeyerR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effects of desloratadine, a potent H1-receptor antagonist, and placebo on nasal airflow, nasal secretion weights, and symptoms of seasonal allergic rhinitis (SAR), including nasal congestion, in patients exposed to grass pollen.
Paper Details　
Original Abstract of the Article :
Nasal congestion is a chronic symptom of seasonal allergic rhinitis (SAR) that is often difficult to treat with antihistamines. Desloratadine, a new, potent, H1-receptor antagonist has been shown to decrease nasal congestion in clinical trials and to maintain nasal airflow in response to grass polle...See full text at original site
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引用元：
https://doi.org/10.1034/j.1398-9995.2003.00148.x

データ提供：米国国立医学図書館（NLM）

Desloratadine: A New Hope for Seasonal Allergic Rhinitis

Seasonal allergic rhinitis (SAR) can be a frustrating condition, often characterized by [nasal congestion]. This study explores the effectiveness of [desloratadine], a new H1-receptor antagonist, in treating SAR. The study compared the effects of [desloratadine 5 mg] to [placebo] in patients exposed to [grass pollen] in a controlled environment. The results demonstrated that [desloratadine] effectively improved [nasal airflow], reduced [nasal secretion weights], and alleviated SAR symptoms, including [nasal congestion].

Desloratadine: A Promising Treatment for Seasonal Allergic Rhinitis

This study provides strong evidence for the efficacy of [desloratadine] in treating SAR. Its ability to improve [nasal airflow] and alleviate [nasal congestion] makes it a valuable treatment option for patients suffering from this common condition.

Relief from Seasonal Allergies

If you struggle with seasonal allergies, discussing [desloratadine] with your doctor may be beneficial. This medication can help alleviate your symptoms, improve your nasal airflow, and reduce the discomfort associated with SAR.

Dr.Camel's Conclusion

Seasonal allergies can be a real nuisance, like a persistent sandstorm blowing across the desert. This study offers a promising solution by demonstrating the effectiveness of [desloratadine] in alleviating SAR symptoms, providing much-needed relief for sufferers.

Date :
  1. Date Completed 2003-10-09
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

12757447

DOI: Digital Object Identifier

10.1034/j.1398-9995.2003.00148.x

Related Literature

Article Analysis
・Effects of desloratadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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