A double-blind comparison of olanzapine versus risperidone in the acute treatment of dementia-related behavioral disturbances in extended care facilities.

Author: FontaineCatherine S, HynanLinda S, KochKathleen, Martin-CookKristin, SvetlikDoris, WeinerMyron F

Paper Details 
Original Abstract of the Article :
BACKGROUND: In addition to demonstrating their superiority to placebo, there is a need to compare the relative efficacy and side effects of atypical neuroleptics for the acute treatment of dementia-related behavioral disturbances in residents of long-term care facilities. METHOD: In a double-blind ...See full text at original site
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引用元:
https://doi.org/10.4088/jcp.v64n0617

データ提供:米国国立医学図書館(NLM)

Olanzapine vs. Risperidone for Dementia-Related Behavioral Disturbances

This double-blind study compares the effectiveness of olanzapine and risperidone in treating dementia-related behavioral disturbances in residents of long-term care facilities. It's like a skilled desert guide comparing two different paths through a challenging landscape, seeking the most effective route to manage behavioral issues in individuals with dementia. The researchers evaluated the efficacy and side effects of these atypical neuroleptics to determine which medication offers the best therapeutic approach.

Equal Efficacy but Different Dosing

The study found that both olanzapine and risperidone were equally effective in reducing behavioral disturbances in individuals with dementia. However, olanzapine required a higher dosage than risperidone to achieve the desired effects. This information is crucial for clinicians to make informed decisions regarding medication selection and dosage titration.

Navigating the Challenges of Dementia Care

This study provides valuable insights into the management of dementia-related behavioral disturbances. It highlights the need for personalized treatment approaches, taking into account individual patient needs and potential side effects. The research underscores the importance of ongoing research to optimize treatment strategies for dementia care.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of olanzapine and risperidone in managing dementia-related behavioral disturbances. While both medications demonstrated equal efficacy, the study highlights the need for careful dosage adjustments and personalized treatment approaches to optimize therapeutic outcomes and minimize side effects. The research underscores the ongoing need for innovative strategies to improve the care of individuals with dementia.

Date :
  1. Date Completed 2003-07-25
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

12823090

DOI: Digital Object Identifier

10.4088/jcp.v64n0617

Related Literature

SNS
PICO Info
in preparation
Languages

English

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