Paper Details

  1. Home
  2. Paper Details

Nandrolone treatment decreases the level of rat kidney alpha(1B)-adrenoceptors.

Author: KindlundhAnna, LindblomJonas, MugishaPaul, NybergFred, UhlénStaffan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effects of the anabolic androgenic steroid nandrolone decanoate on renal alpha-adrenoceptors in rats. The results showed a significant reduction in kidney alpha(1B)-adrenoceptors, which may contribute to the hypertension and fluid retention associated with AAS abuse.
Paper Details　
Original Abstract of the Article :
Abuse of anabolic androgenic steroids (AAS) is associated with serious side effects, such as hypertension and fluid retention. Renal alpha(1)- and alpha(2)-adrenoceptors are implicated in the regulation of blood pressure and fluid balance. In the present study, the levels of renal alpha(1A)-, alpha(...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s00210-003-0763-y

データ提供：米国国立医学図書館（NLM）

Nandrolone Treatment: Impact on Kidney Alpha(1B)-Adrenoceptors

This research explores the potential impact of nandrolone, an anabolic androgenic steroid, on kidney alpha(1)-adrenoceptors. The study found that nandrolone treatment significantly reduced the levels of kidney alpha(1B)-adrenoceptors in rats. This finding suggests that nandrolone may contribute to side effects associated with anabolic steroid abuse, such as hypertension and fluid retention.

Nandrolone: A Potential Contributor to Anabolic Steroid Side Effects

This research highlights the potential risks associated with anabolic steroid abuse. The reduction in kidney alpha(1B)-adrenoceptors observed in the study suggests that nandrolone could play a role in the development of side effects. It's like a desert mirage, where a seemingly harmless oasis can lead to dangerous consequences.

Nandrolone: A Cautionary Tale About Anabolic Steroid Abuse

This research serves as a reminder of the potential dangers of anabolic steroid abuse. The findings highlight the importance of understanding the potential consequences of using these substances and seeking professional advice before considering their use. It's like navigating a treacherous desert, where every step must be carefully considered to avoid hidden dangers.

Dr. Camel's Conclusion

This research underscores the importance of scientific understanding in navigating the complexities of drug use. Like a wise camel, we must carefully consider the potential consequences of our actions before embarking on a journey that could lead to unforeseen dangers.

Date :
  1. Date Completed 2004-06-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

12861436

DOI: Digital Object Identifier

10.1007/s00210-003-0763-y

Related Literature

Article Analysis
・Side Effects of prazosin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.