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Phenelzine efficacy in refractory social anxiety disorder: a case series.

Author: AarreTrond F

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Phenelzine was effective in treating social phobia that was unresponsive to other treatments. Six out of seven patients responded to treatment, and there were no serious adverse events.
Paper Details　
Original Abstract of the Article :
Several effective treatments for social phobia are now available, notably cognitive behavioural therapy and some antidepressant medications. Controlled trials indicate that 25-45% of patients fail to respond to the initial treatment. To my knowledge, nothing has yet been published on the treatment o...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12888407

データ提供：米国国立医学図書館（NLM）

Phenelzine for Refractory Social Anxiety Disorder

Social anxiety disorder (SAD) can have a profound impact on an individual's life, often leading to social isolation and impaired quality of life. This study explores the potential of phenelzine, a monoamine oxidase inhibitor (MAOI) antidepressant, as a treatment option for patients with SAD who have not responded to other therapies. The authors present a case series of seven patients with refractory SAD who were treated with phenelzine.

Phenelzine Offers Hope for Refractory Cases

The study found that six out of the seven patients experienced significant improvement in their SAD symptoms while taking phenelzine. These findings suggest that phenelzine may be a valuable treatment option for individuals with SAD who have not responded to conventional therapies. The authors emphasize that phenelzine should be considered as a treatment option for patients with treatment-resistant SAD.

Managing Side Effects

The study acknowledges that phenelzine can have side effects, such as somnolence and vomiting. However, the authors note that these side effects were generally mild and transient. They emphasize that the potential benefits of phenelzine may outweigh the risks for patients with severe SAD who have not responded to other treatments.

Dr.Camel's Conclusion

Social anxiety disorder can be a lonely desert to traverse. This study offers a glimmer of hope for those struggling with refractory SAD, suggesting that phenelzine may be a valuable tool in their journey towards recovery.

Date :
  1. Date Completed 2004-01-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12888407

DOI: Digital Object Identifier

9T50NU84V8R8JPDM

Related Literature

Article Analysis
・Side Effects of phenelzine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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