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Chemotherapy of advanced epithelial cancer--a critical review.

Author: AbelU

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A review of clinical trials found that chemotherapy does not consistently prolong survival for patients with advanced epithelial cancer, except for lung cancer (especially small-cell lung cancer) and ovarian cancer. Even in these cases, the benefits of chemotherapy are minimal, and less aggressive approaches may be equally effective. There is no clear evidence that responding to chemotherapy improves survival. The impact of chemotherapy on quality of life for patients with advanced cancer is unclear. The study calls for more research to determine the optimal use of chemotherapy in advanced epithelial cancers, including studies comparing different doses and timing of treatment, as well as its value in symptom-free patients.
Paper Details　
Original Abstract of the Article :
This article is a short version of a report which presents a comprehensive analysis of clinical trials and publications examining the value of cytotoxic chemotherapy in the treatment of advanced epithelial cancer. As a result of the analysis and the comments received from hundreds of oncologists in ...See full text at original site
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引用元：
https://doi.org/10.1016/0753-3322(92)90002-o

データ提供：米国国立医学図書館（NLM）

Chemotherapy for Advanced Epithelial Cancer

The fight against cancer is a complex and challenging journey, often requiring a combination of treatments and therapies. This research explores the role of cytotoxic chemotherapy in the treatment of advanced epithelial cancer. The study provides a critical review of clinical trials and publications, offering valuable insights into the effectiveness of chemotherapy in this context.

The Complexities of Chemotherapy in Advanced Epithelial Cancer

The study concludes that, with the exception of lung cancer, there is no direct evidence that chemotherapy prolongs survival in patients with advanced carcinoma. The study highlights the need for further research to determine the effectiveness of chemotherapy for specific types of advanced epithelial cancer and to identify subgroups of patients who may benefit from this treatment.

Understanding the Limitations of Chemotherapy

This research underscores the importance of understanding the limitations of chemotherapy. It's like navigating a desert – you need to be aware of potential pitfalls and choose the right path based on individual needs and circumstances.

Dr. Camel's Conclusion

This study emphasizes the need for a nuanced approach to chemotherapy in the treatment of advanced epithelial cancer. It's like navigating a desert – you need to carefully consider the terrain and choose the right tools for the journey.

Date :
  1. Date Completed 1993-08-09
  2. Date Revised 2019-10-21
Further Info :

Pubmed ID

1339108

DOI: Digital Object Identifier

10.1016/0753-3322(92)90002-o

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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