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Ocular side-effects in breast cancer patients treated with tamoxifen and toremifene: a randomized follow-up study.

Author: , HolliK, PaakkalaA-M, ParkkariM, SalminenL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tamoxifen and toremifene are anti-estrogens used to treat breast cancer. While they have known side effects, this study investigates their potential ocular side effects.
Paper Details　
Original Abstract of the Article :
3Tamoxifen and toremifene are non-steroidal anti-oestrogens widely used in the treatment of advanced breast cancer and as adjuvant therapy following surgery in early stage disease. Tamoxifene has also been approved for use in reducing the incidence of breast cancer amongst high risk women. However, ...See full text at original site
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引用元：
https://doi.org/10.1034/j.1600-0420.2003.00116.x

データ提供：米国国立医学図書館（NLM）

Monitoring Ocular Side Effects of Tamoxifen and Toremifene

This research delves into the potential ocular side effects of tamoxifen and toremifene, two commonly used anti-estrogens in breast cancer treatment. The researchers, like explorers navigating a vast desert of potential adverse effects, sought to assess the safety of these drugs. Their findings, like oases in the desert, provide valuable information for clinicians and patients. They observed that both tamoxifen and toremifene can cause a range of ocular side effects, such as blurred vision and dry eyes, although the severity and frequency varied. This information is crucial for informing treatment decisions and ensuring patient well-being.

The Importance of Vigilance in Breast Cancer Treatment

This research highlights the importance of vigilance in monitoring for potential side effects of breast cancer treatments. The study's findings underscore the need for open communication between clinicians and patients, enabling early detection and management of any adverse effects. This approach can help to minimize the impact of side effects on patient quality of life and ensure optimal treatment outcomes.

Patient Safety and Treatment Optimization

The research underscores the importance of balancing the benefits and risks of breast cancer treatment. While tamoxifen and toremifene offer valuable therapeutic options, clinicians and patients must be aware of the potential for ocular side effects. By carefully monitoring for these effects and implementing appropriate management strategies, healthcare providers can optimize treatment outcomes and ensure patient safety.

Dr. Camel's Conclusion

This research, like a camel caravan navigating the desert of breast cancer treatment, emphasizes the importance of monitoring potential side effects. The findings highlight the need for open communication, patient education, and a proactive approach to managing ocular side effects, ensuring patient safety and optimal treatment outcomes.
Date :
  1. Date Completed 2003-12-11
  2. Date Revised 2019-09-22
Further Info :

Pubmed ID

14510798

DOI: Digital Object Identifier

10.1034/j.1600-0420.2003.00116.x

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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