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New drugs for the treatment of hypercholesterolaemia.

Author: DíezJuan J, IglesiasPedro

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review discusses the various lipid-lowering drugs used to reduce the risk of coronary heart disease. The review highlights two new statins, rosuvastatin and pitavastatin, which are more potent than other available statins and have a lower risk of muscle toxicity. The review also discusses the use of ezetimibe, a selective cholesterol absorption inhibitor, and colesevelam, a bile acid sequestrant.
Paper Details　
Original Abstract of the Article :
Endogenous and exogenous pathways determine plasma levels of cholesterol and lipoproteins. Plasma cholesterol levels and coronary heart disease risk can be reduced pharmacologically by decreasing cholesterol synthesis, increasing its elimination and/or reducing its absorption from the intestine. The...See full text at original site
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引用元：
https://doi.org/10.1517/13543784.12.11.1777

データ提供：米国国立医学図書館（NLM）

New Hope for Hypercholesterolemia: A Look at Emerging Lipid-Lowering Drugs

[Hypercholesterolemia], elevated cholesterol levels, is a major risk factor for cardiovascular disease. This study examines the development of new drugs for treating hypercholesterolemia, focusing on their mechanisms of action and potential benefits.

Expanding the Therapeutic Arsenal for Hypercholesterolemia

The study highlights the development of new lipid-lowering drugs targeting different aspects of cholesterol metabolism, including cholesterol synthesis, elimination, and intestinal absorption. These drugs offer promising approaches to reducing cholesterol levels and mitigating the risks associated with hypercholesterolemia.

Innovations in Lipid-Lowering Therapy

This research underscores the advancements in lipid-lowering therapy, with the development of novel drugs like statins, cholesterol absorption inhibitors, and bile acid sequestrants. These innovations offer more targeted and effective approaches to managing hypercholesterolemia, improving cardiovascular health and reducing the risk of heart disease.

Dr.Camel's Conclusion

Imagine a desert caravan traveling through a vast landscape. Hypercholesterolemia is like a sandstorm that can hinder the caravan's journey. This study explores new tools to combat this sandstorm, offering potential remedies to protect cardiovascular health and ensure a smoother journey through life.

Date :
  1. Date Completed 2004-03-18
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

14585054

DOI: Digital Object Identifier

10.1517/13543784.12.11.1777

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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