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Evaluating minimal clinically important differences for the acne-specific quality of life questionnaire.

Author: BrandmanJane, FehnelSheri E, McLeodLori D, SymondsTara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study using the Acne-Specific Quality of Life Questionnaire (Acne-QoL) showed statistically significant improvements in quality of life for women with moderate acne who used a low-dose oral contraceptive (Estrostep) compared to placebo. However, the study questions whether these statistically significant results translate to meaningful improvements in daily life.
Paper Details　
Original Abstract of the Article :
The Acne-Specific Quality of Life Questionnaire (Acne-QoL) is a responsive, reliable and valid instrument developed to measure the impact of facial acne across four dimensions of patient QOL. Score changes on this instrument have been used to report statistically significant treatment advantages for...See full text at original site
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引用元：
https://doi.org/10.2165/00019053-200321150-00001

データ提供：米国国立医学図書館（NLM）

Acne-Specific Quality of Life Questionnaire (Acne-QoL): Measuring the Impact of Acne on Patient Well-being

This research focuses on the Acne-Specific Quality of Life Questionnaire (Acne-QoL), a validated instrument designed to measure the impact of facial acne on patient quality of life (QoL). The study explored the clinical meaningfulness of statistically significant treatment advantages observed with a low-dose oral contraceptive compared to placebo in women with moderate acne vulgaris. The authors aim to determine whether these statistically significant results translate into clinically meaningful improvements in QoL.

Beyond Statistics: Assessing the Clinical Impact of Acne Treatment

The study highlights the importance of evaluating treatment effectiveness not only statistically but also in terms of its impact on patient QoL. This underscores the need for patient-reported outcome measures, such as the Acne-QoL, to provide a more comprehensive understanding of treatment outcomes. The study’s findings emphasize the importance of considering both statistical significance and clinical meaningfulness when assessing the efficacy of acne treatments.

The Human Cost of Acne: Beyond Skin Deep

This study serves as a reminder that acne, beyond its physical manifestation, can have a significant impact on patient QoL. Understanding the psychological and social implications of acne can help healthcare professionals provide more holistic and patient-centered care. This research highlights the importance of utilizing tools like the Acne-QoL to measure the impact of acne on patient well-being and to guide treatment decisions.

Dr. Camel's Conclusion

The Acne-QoL provides a valuable tool for measuring the impact of acne on patient QoL and for evaluating the clinical meaningfulness of treatment outcomes. This research underscores the importance of considering both statistical significance and clinical impact when assessing acne treatments, ultimately aiming to improve patient well-being and quality of life.

Date :
  1. Date Completed 2003-12-04
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

14596626

DOI: Digital Object Identifier

10.2165/00019053-200321150-00001

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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