Paper Details

  1. Home
  2. Paper Details

[Pharmacotherapy in heroin addiction: pharmacological approaches to remission stabilization and recurrence prevention].

Author: GrinenkoA Ia, KrupitskiĭE M, ZvartauE E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study investigated the effectiveness of citalopram (SSRI) and memantine (NMDA receptor antagonist) in treating anhedonia in heroin addicts, finding that both drugs effectively arrested anhedonia symptoms. Naltrexone was found to be more effective for remission stabilization, while a combination of naltrexone with SSRI antidepressants showed promise for both remission stabilization and recurrence prevention.
Paper Details　
Original Abstract of the Article :
After withdrawal arrest in many heroin addicts, they displayed the syndrome of anhedonia including affective disorders (depression, dysphoria, anxiety), dyssomnia and a pathologic craving for opiates. Anhedonia is often the cause for recurrence in heroine addiction, therefore, an appropriate treatme...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/14598513

データ提供：米国国立医学図書館（NLM）

Heroin Addiction: A Complex Challenge Requiring Multifaceted Solutions

Heroin addiction is a serious public health issue that presents a complex challenge for treatment and recovery. This research explores different pharmacological approaches to address heroin addiction, focusing on remission stabilization and recurrence prevention. The study investigates the effectiveness of various medications in managing withdrawal symptoms, cravings, and relapse.

Navigating the Path to Recovery: A Multi-Drug Approach

The researchers examined the efficacy of different medications in managing heroin addiction, including selective serotonin reuptake inhibitors (SSRIs), NMDA receptor antagonists, and naltrexone. The study found that a combination of naltrexone (blocking the effects of heroin and reducing relapse rates) with SSRI antidepressants (effectively addressing anhedonia symptoms and improving compliance with naltrexone medication) was the most promising approach to remission stabilization and recurrence prevention.

Harnessing the Power of Pharmacology

This research underscores the importance of developing effective pharmacological treatments for heroin addiction. Imagine a weary traveler in the vast desert seeking refuge and guidance. Just as a compassionate guide provides support and direction, medications can play a crucial role in helping individuals overcome addiction and achieve lasting recovery.

Dr. Camel's Conclusion

Heroin addiction is a formidable foe, but this research offers hope by highlighting the potential of pharmacological approaches to address this complex issue. The findings provide valuable insights into the complex interplay of medications and addiction, guiding us towards more effective treatment strategies. As we continue to explore the depths of addiction research, we must remain dedicated to finding innovative solutions to help those seeking a path to recovery.

Date :
  1. Date Completed 2004-03-19
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

14598513

DOI: Digital Object Identifier

14598513

Related Literature

Article Analysis
・Effective treatment of heroin
SNS
PICO Info
in preparation
Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.