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[Changes in lipid status during pravastatin treatment].

Author: AltomareS, CitellaC, ColomboL, CraveriA, GiavardiL, LanfrediniM, PedrazziniL, PicolloS, VignatiA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Statins, specific inhibitors of HMG-CoA-reductase, are effective in lowering cholesterol levels. A study investigated the efficacy and tolerability of pravastatin compared to gemfibrozil for long-term use in patients with high cholesterol levels.
Paper Details　
Original Abstract of the Article :
Reduced cholesterolemia lowers the risk of ischemic cardiopathy, especially if LDL cholesterol levels are reduced. Today this effect can be achieved using drugs following the discovery of a new class of molecules: statins are specific inhibitors of HMG-CoA-reductase, a key enzyme in cholesterol bios...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1461540

データ提供：米国国立医学図書館（NLM）

Pravastatin: A New Hope for Reducing Cholesterol Levels

High cholesterol levels are a significant risk factor for cardiovascular disease, a leading cause of death worldwide. This study evaluated the efficacy and tolerability of pravastatin, a statin medication used to lower cholesterol levels. The researchers compared the effects of pravastatin with those of gemfibrozil, another cholesterol-lowering medication, in patients with high cholesterol levels.

Pravastatin: An Effective and Well-Tolerated Treatment Option

The study confirmed that pravastatin was effective and well-tolerated for long-term use in patients with high cholesterol levels. It demonstrated that pravastatin was comparable to gemfibrozil in its ability to reduce cholesterol levels, offering a viable alternative for managing hypercholesterolemia.

A New Pathway to Cardiovascular Health: Navigating the Desert of Heart Disease

This study highlights the importance of cholesterol management in preventing cardiovascular disease. It underscores the effectiveness and safety of pravastatin as a treatment option for high cholesterol levels, offering a new path towards cardiovascular health. The desert of heart disease research continues to expand, revealing new and innovative approaches to prevent and manage this debilitating condition.

Dr.Camel's Conclusion

The desert of cardiovascular disease is vast and unforgiving, but new research continues to emerge, offering a glimmer of hope for better management and prevention. This study highlights the effectiveness and safety of pravastatin as a treatment for high cholesterol levels, paving the way for a healthier future for individuals at risk of cardiovascular disease.

Date :
  1. Date Completed 1993-01-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1461540

DOI: Digital Object Identifier

1461540

SNS
PICO Info
in preparation
Languages

Italian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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