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Improvement in postoperative pain relief by the addition of midazolam to an intrathecal injection of buprenorphine and bupivacaine.

Author: GoodchildC S, HalbeA R, PanchalI D, ShahF R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study compared the effectiveness of adding midazolam to a mixture of buprenorphine and bupivacaine for spinal anesthesia. Intrathecal midazolam has been shown to provide antinociception and pain relief in animals and humans, including potentiation of opioid analgesia.
Paper Details　
Original Abstract of the Article :
Intrathecal injections of the benzodiazepine midazolam have been reported to cause antinociception in animals and pain relief in human beings, including the potentiation of opioid analgesia. This study compared the efficacy of the addition of midazolam to a mixture of buprenorphine and bupivacaine u...See full text at original site
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引用元：
https://doi.org/10.1017/s0265021503001455

データ提供：米国国立医学図書館（NLM）

Pain Relief: A Desert Oasis of Comfort

Postoperative pain is a common and unwelcome experience, often hindering recovery and impacting quality of life. This research explores the potential of combining midazolam, a benzodiazepine, with a mixture of buprenorphine and bupivacaine, commonly used for spinal anesthesia, to enhance pain relief. The study examines the efficacy of this combination in reducing postoperative pain, comparing it to the use of buprenorphine and bupivacaine alone.

The Power of Combinations: A Desert Oasis of Relief

The study reveals that adding midazolam to the anesthetic cocktail can significantly improve postoperative pain relief. This finding highlights the potential of combining different medications to achieve more effective pain management. It's like discovering a hidden oasis in the desert: Combining different sources of water can create a more bountiful and enduring source of hydration.

Finding Comfort: Navigating the Desert of Pain

This research offers hope for patients seeking effective pain relief after surgery. It's like finding a hidden oasis in the desert of postoperative pain, offering a chance for greater comfort and a smoother recovery. The study underscores the importance of exploring different approaches to pain management and seeking solutions tailored to individual needs.

Dr. Camel's Conclusion

This research provides a valuable reminder that even in the arid landscape of postoperative pain, there are hidden oases of relief waiting to be discovered. By combining different approaches and exploring innovative solutions, we can provide greater comfort to patients during their recovery journeys. It's a testament to the power of collaboration and ingenuity in the quest for pain relief.

Date :
  1. Date Completed 2004-04-22
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

14649343

DOI: Digital Object Identifier

10.1017/s0265021503001455

Related Literature

Article Analysis
・Effects of buprenorphine injection (pain relief)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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