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Chemical systems for delivery of antiepileptic drugs to the central nervous system.

Author: BodorN, PopE

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A chemical delivery system (CDS) was developed to enhance drug uptake in the central nervous system (CNS). The CDS, based on dihydropyridine<-->pyridinium salt type redox targetors, improved brain uptake and pharmacologic activity of antiepileptic drugs without any observed toxic side effects.
Paper Details　
Original Abstract of the Article :
The chemical delivery system (CDS) approach, a recently developed procedure conceived to enhance the specific central nervous system (CNS) uptake of drugs, has been applied to several antiepileptic agents. CDSs based on dihydropyridine<-->pyridinium salt type redox targetors, reversibly linked to th...See full text at original site
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引用元：
https://doi.org/10.1016/0920-1211(92)90002-b

データ提供：米国国立医学図書館（NLM）

Chemical Delivery Systems for Antiepileptic Drugs: A Promising Approach

In the field of [neurology], researchers are constantly seeking ways to improve the delivery and efficacy of medications. This study explores the potential of [chemical delivery systems (CDSs)] to enhance the delivery of [antiepileptic drugs] to the [central nervous system (CNS)]. The researchers focused on [dihydropyridine<-->pyridinium salt type redox targetors] as a novel approach to improve drug targeting and effectiveness.

Potential for Improved Drug Delivery and Efficacy

The researchers' findings suggest that [CDSs] have the potential to improve the [brain uptake] and [pharmacologic activity] of [antiepileptic drugs]. These findings hold promise for the development of more effective and targeted therapies for [epilepsy] and other [CNS disorders].

A More Effective Treatment for Epilepsy

If successful, this approach could lead to a significant improvement in the treatment of [epilepsy]. Imagine a world where [epileptic seizures] can be better controlled, allowing individuals to live fuller and more independent lives. The development of [CDSs] for [antiepileptic drugs] represents a promising step towards this goal.

Dr.Camel's Conclusion

This study highlights the ingenuity of [researchers] in the field of [neurology]. Just as a camel navigates the intricate pathways of the desert, researchers are constantly seeking new routes to improve drug delivery and treatment outcomes. The development of [CDSs] represents a promising path forward in the treatment of [epilepsy] and other [CNS disorders]. The researchers' findings inspire optimism for a future where [epileptic seizures] are better controlled and lives are transformed.

Date :
  1. Date Completed 1993-02-08
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

1478193

DOI: Digital Object Identifier

10.1016/0920-1211(92)90002-b

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English

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