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Influence of carteolol and timolol on IOP an visual fields in glaucoma: a multi-center, double-masked, prospective study.

Author: BonomiL, ChavyB, ChevallierB, DorigoM T, FlammerJ, FsadniM, JournelB, KitazawaY, MillsB, ShiratoS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both Carteolol and Timolol eye drops significantly reduced intraocular pressure (IOP) without affecting visual fields. Both drugs were well-tolerated with minimal side effects.
Paper Details　
Original Abstract of the Article :
The influences of Carteolol and Timolol eye drops on intraocular pressure (IOP) and visual fields were compared in a multi-center, double-masked, prospective study. Two-hundred and forty eyes of 120 patients were initially included in the study, and 142 eyes of 72 patients fulfilled all the criteria...See full text at original site
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引用元：
https://doi.org/10.1177/112067219200200402

データ提供：米国国立医学図書館（NLM）

The Battle for Intraocular Pressure: A Multi-Center Showdown Between Carteolol and Timolol

Glaucoma is a serious eye condition that can lead to irreversible vision loss. This study investigates the efficacy and safety of two beta-blocker eye drops, carteolol and timolol, in managing intraocular pressure (IOP) in patients with glaucoma. The study involved a multi-center, double-masked, prospective design, allowing researchers to compare the effects of both drugs on IOP and visual fields over a one-year period.

A Tale of Two Beta-Blockers: A Balancing Act for Glaucoma Management

The research found that both carteolol and timolol significantly reduced IOP, indicating their efficacy in managing this key aspect of glaucoma. The study did not observe any significant changes in visual fields in either treatment group, suggesting that both drugs were effective in preventing further progression of visual field defects. The researchers noted that while some patients experienced minor improvements or deteriorations in visual fields, these changes were not statistically significant. The study also found that both drugs were well-tolerated, with minimal side effects and no significant differences in their frequency or intensity between the two treatment groups.

A Glimpse into Glaucoma Management: Choosing the Right Weapon

This research provides valuable insights into the treatment of glaucoma. The study's findings suggest that both carteolol and timolol are effective in reducing IOP and preventing further progression of visual field defects. The decision of which drug to use should be made on a case-by-case basis, taking into account individual patient factors such as tolerance, side effects, and other medical conditions.

Dr.Camel's Conclusion

This research reinforces the effectiveness of beta-blockers in managing IOP in patients with glaucoma. The study's findings demonstrate that both carteolol and timolol are safe and effective options, providing valuable information for ophthalmologists to make informed treatment decisions.

Date :
  1. Date Completed 1993-03-04
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

1490088

DOI: Digital Object Identifier

10.1177/112067219200200402

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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