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Haloperidol and lorazepam combined: clinical effects and drug plasma levels in the treatment of acute schizophrenic psychosis.

Author: GaertnerH J, MahalA, StevensA, StevensI

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Lorazepam, combined with haloperidol, did not show any improvement in psychopathology or faster resolution of symptoms compared to haloperidol alone in acute schizophrenic patients.
Paper Details　
Original Abstract of the Article :
In 61 acute schizophrenic patients the effects of haloperidol (HPL) and lorazepam combined vs. HPL alone and the interaction between these drugs were evaluated. Patients were assigned to groups randomly. The study design was open. Study duration was 28 days. Psychopathology was evaluated on the basi...See full text at original site
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引用元：
https://doi.org/10.1055/s-2007-1014421

データ提供：米国国立医学図書館（NLM）

Unraveling the Mystery of Combined Medications

The world of mental health is full of complex mysteries, and the treatment of acute schizophrenic psychosis is no exception. This study delves into the effectiveness of combining haloperidol and lorazepam, two common medications used to treat psychosis. Like a desert explorer seeking hidden treasures, the researchers embarked on a 28-day journey to evaluate the impact of this combination on patients. They found that the combination didn't provide any significant benefits compared to haloperidol alone. This discovery is similar to a desert wanderer realizing that a shortcut they thought would lead to an oasis is actually a dead end. It emphasizes the importance of carefully evaluating medication combinations to ensure they truly provide the desired benefits.

Finding the Right Oasis in Mental Health Treatment

The study's findings suggest that combining haloperidol and lorazepam may not be the most effective approach to treating acute psychosis. The study showed no difference in efficacy between the combination and haloperidol alone. It's like realizing that the combined desert oasis isn't as appealing as you initially thought. This research underscores the need for careful consideration and individualization when choosing treatments for mental health conditions, emphasizing the importance of personalized approaches and further research to uncover the most effective treatment strategies.

The Desert of Mental Health

The complex landscape of mental health requires careful navigation. This study highlights the importance of evaluating medication combinations to ensure their effectiveness. It serves as a reminder that the journey to improved mental health can be long and winding, requiring a keen eye for the best treatment paths.

Dr.Camel's Conclusion

The research on combined medication for psychosis is a testament to the complexities of mental health. It highlights the importance of carefully considering the effectiveness of treatment combinations to ensure the best possible outcomes for patients. It's like a desert journey, where choosing the right path is crucial to reach the desired destination.

Date :
  1. Date Completed 1993-03-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1494594

DOI: Digital Object Identifier

10.1055/s-2007-1014421

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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