Nonobese women with polycystic ovary syndrome respond better than obese women to treatment with metformin.

Author: Abi HaidarMauro, Alves da MottaEduardo Leme, BaracatEdmund C, MacielGustavo Arantes Rosa, Soares JúniorJosé Maria, de LimaGeraldo Rodrigues

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To determine the clinical, hormonal, and biochemical effects of metformin therapy in obese and nonobese patients with polycystic ovary syndrome (PCOS). DESIGN: Controlled clinical study. SETTING: Department of Gynecology of Federal University of São Paulo, São Paulo, Brazil. PATIENT(S)...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/14967373

データ提供:米国国立医学図書館(NLM)

Metformin: A More Effective Treatment for Nonobese Women

This study explores the [endocrinology] and [pharmacology] of metformin, a medication commonly used to manage type 2 diabetes, and its effectiveness in treating polycystic ovary syndrome (PCOS) in obese and nonobese women. PCOS, like a desert with a disrupted water cycle, can affect a woman's hormonal balance and fertility. This study investigates whether metformin, like a well-timed rainfall, can help restore balance in the body.

The study, involving 29 women with PCOS, found that nonobese women responded better to metformin therapy compared to obese women. Nonobese women treated with metformin showed significant reductions in insulin levels, testosterone levels, and improved hormonal profiles. It's a bit like a desert that is more receptive to rainfall when the soil is drier and less compacted.

A Targeted Approach to Treatment

This study highlights the importance of considering individual factors, such as body mass index, when treating PCOS. It's a reminder that, like navigating a desert, different approaches are needed depending on the specific conditions.

Improving Fertility and Hormonal Balance

This research provides valuable insights into the potential of metformin for treating PCOS and improving fertility. It's a reminder that, like a desert that can bloom with life after a nourishing rainfall, the human body can benefit from the right interventions.

Dr. Camel's Conclusion

This study underscores the importance of personalized medicine and considering individual factors when treating PCOS. It's a reminder that, like a desert that needs the right conditions for life to thrive, the human body requires tailored approaches for optimal health.

Date :
  1. Date Completed 2004-03-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

14967373

DOI: Digital Object Identifier

S0015028203028528

Related Literature

SNS
PICO Info
in preparation
Languages

English

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