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Two doses of oral sustained-release tramadol do not reduce pain or morphine consumption after modified radical mastectomy: a randomized, double blind, placebo-controlled trial.
Author: KlaichanadChongsuk, KrisanaprakornkitWimonrat, TaesiriWorranut, ThaninsuratNuanchan, ThienthongSomboon, UtsahapanichSiriporn
Original Abstract of the Article :
Tramadol is a weak opioid agonist with antinociceptive effects through its action on the mu-receptor and by inhibiting the neuronal re-uptake of both noradrenaline and serotonin. Tramadol is commonly used for treatment of mild to moderate post-operative pain. An oral form of sustained-release tramad...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/14971531
データ提供:米国国立医学図書館(NLM)
A Quest for Pain Relief: Tramadol's Journey in Modified Radical Mastectomy
The quest for pain relief after surgery is a constant challenge, much like navigating a treacherous desert. This study examines the effectiveness of tramadol, a weak opioid agonist, in managing post-operative pain following modified radical mastectomy, a procedure commonly used to treat breast cancer. The authors conducted a double-blind, placebo-controlled trial, comparing the effects of two doses of sustained-release tramadol (SR) to placebo. The results of their journey through the desert of pain relief are revealing: despite tramadol's potential, the study did not find a significant reduction in pain or morphine consumption in the treatment group. This study underscores the need for further exploration of pain management strategies following breast cancer surgery, seeking alternative pathways to provide effective relief for those navigating this difficult terrain.The Search for a Pain-Free Oasis
The study's findings highlight the complex nature of post-operative pain management, emphasizing the need for continued research into alternative approaches. It's like searching for an elusive oasis in a vast desert, requiring persistence and a willingness to explore new possibilities. Further exploration of different medications and pain management techniques is crucial to provide effective relief for those seeking solace from the desert of post-operative pain.Navigating the Desert of Pain
As a desert wanderer, I've experienced the harshness of pain and the relentless pursuit of relief. This study resonates with me, emphasizing the ongoing challenge of providing effective pain management for those facing difficult medical journeys. It's like searching for a cool spring in a barren desert, a quest that requires dedication and innovation.Dr. Camel's Conclusion
This study explores the use of tramadol in managing post-operative pain after modified radical mastectomy. While the results do not show significant pain relief, the research highlights the need for further exploration of effective pain management strategies, emphasizing the importance of finding a path towards a pain-free oasis for those navigating this challenging terrain.Date :
- Date Completed 2004-03-12
- Date Revised 2013-11-21
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