Paper Details

  1. Home
  2. Paper Details

Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine.

Author: DienerH C, MacGregorE A, MuirheadsN, SchoenenJ, SikesC R, SteinerT J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effectiveness of eletriptan (80mg and 40mg) and zolmitriptan in treating acute migraine attacks. Eletriptan was more effective in relieving headache pain and reducing the need for rescue medication.
Paper Details　
Original Abstract of the Article :
Eletriptan 40 mg and 80 mg have shown greater efficacy in acute migraine than oral sumatriptan 100 mg and naratriptan 2.5 mg. This study continues the systematic series of active comparator trials in the eletriptan clinical development programme. In a multicentre double-blind, double-dummy, parallel...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1046/j.1468-2982.2003.00617.x

データ提供：米国国立医学図書館（NLM）

Comparative Efficacy of Eletriptan and Zolmitriptan for Migraine

Migraine, a debilitating headache disorder, significantly impacts quality of life. This study compares the efficacy of eletriptan, a triptan medication used for acute migraine treatment, with zolmitriptan, another commonly used triptan. The researchers conducted a double-blind, randomized trial to assess the effectiveness of these medications in relieving migraine headaches.

Eletriptan's Superior Efficacy: A Beacon of Hope for Migraine Sufferers

The results indicate that eletriptan 80 mg was superior to zolmitriptan 2.5 mg in relieving migraine headaches, with significantly higher rates of headache response at various time points. Eletriptan 40 mg demonstrated comparable efficacy to zolmitriptan but with lower recurrence rates and a reduced need for rescue medications. This study suggests that eletriptan may be a more effective treatment option for acute migraine.

Finding Relief from Migraine: Navigating the Sands of Treatment Options

The study emphasizes the importance of selecting the right medication for individual migraine patients. The findings demonstrate that eletriptan may offer significant benefits over zolmitriptan for many individuals, highlighting the need for individualized treatment approaches for this complex condition.

Dr.Camel's Conclusion

This study, like a desert guide leading travelers to a hidden oasis, provides valuable information on the comparative efficacy of eletriptan and zolmitriptan for migraine treatment. The findings offer insights into the potential benefits of eletriptan for a subset of migraine sufferers, suggesting a new avenue for alleviating the debilitating effects of this common condition.
Date :
  1. Date Completed 2004-03-31
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

14984226

DOI: Digital Object Identifier

10.1046/j.1468-2982.2003.00617.x

Related Literature

Article Analysis
・Effects of eletriptan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.