Paper Details

  1. Home
  2. Paper Details

Diuretics: drugs of choice for the initial management of patients with hypertension.

Author: FuchsFlávio D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The study discusses the importance of diuretics as first-line treatment for hypertension, citing the findings of the ALLHAT trial, which showed that diuretics are equivalent to other antihypertensive drugs in preventing heart attacks and have advantages in preventing other complications.
Paper Details　
Original Abstract of the Article :
The optimal first-line treatment of hypertension has been a contentious issue. Despite the probable advantage of diuretics, which was demonstrated in early clinical trials, concern about their metabolic effects meant that therapy was often commenced with drugs of other types. The results of the Anti...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1586/14779072.1.1.35

データ提供：米国国立医学図書館（NLM）

Diuretics: Drugs of Choice for the Initial Management of Patients with Hypertension

This study revisits a long-debated issue in hypertension management: the optimal first-line treatment strategy. The authors argue for the effectiveness and practicality of diuretics as the initial treatment of choice for hypertension, emphasizing their role in preventing major cardiovascular events.

Diuretics: A Powerful Tool for Combating Hypertension

The study underscores the efficacy of diuretics in controlling hypertension, drawing upon the findings of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), which demonstrated the equivalence between diuretics and other antihypertensive drug classes in preventing cardiovascular events. The diuretic even surpassed other drugs in preventing certain secondary end-points, such as cerebrovascular disease and heart failure.

Navigating the Desert of Hypertension Management

The study provides valuable insights for healthcare professionals managing hypertension, suggesting a return to diuretics as a key initial treatment option. It's like rediscovering a well-established oasis in the desert of hypertension management, offering a safe and effective strategy for managing this prevalent health condition.

Dr.Camel's Conclusion

This study highlights the significant role of diuretics in hypertension management, offering a reliable and cost-effective tool for combating this widespread health concern. It's a reminder that sometimes, the most effective solutions lie in revisiting and re-evaluating established therapies, especially in the vast and complex desert of cardiovascular medicine.

Date :
  1. Date Completed 2004-05-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15030295

DOI: Digital Object Identifier

10.1586/14779072.1.1.35

Related Literature

Article Analysis
・Side Effects of chlorthalidone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.