Sertraline versus paroxetine in the treatment of panic disorder: an acute, double-blind noninferiority comparison.

Author: AlkinTunc, BandelowBorwin, BehnkeKirsten, ClaryCathryn M, GoebelClaus, HendriksG J, LenoirSergio

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Several classes of medications have demonstrated efficacy in panic disorder, but direct comparison of 2 proven treatments is still uncommon. The purpose of this study was to compare sertraline and paroxetine in the acute treatment of panic disorder. METHOD: Adult outpatients with panic d...See full text at original site
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引用元:
https://doi.org/10.4088/jcp.v65n0317

データ提供:米国国立医学図書館(NLM)

Sertraline vs. Paroxetine: Navigating the Desert of Panic Disorder

This study compares the efficacy and tolerability of sertraline and paroxetine in the acute treatment of panic disorder. The researchers conducted a double-blind, noninferiority trial, randomly assigning patients to receive either sertraline or paroxetine for 12 weeks. The findings indicated that both sertraline and paroxetine were equally effective in reducing panic symptoms, with similar rates of improvement on various outcome measures. However, sertraline was associated with better tolerability and less clinical worsening during the medication taper period.

Sertraline vs. Paroxetine: Navigating the Desert of Panic Disorder

This study delves into the world of panic disorder, comparing two commonly prescribed medications, sertraline and paroxetine. The researchers found that both medications were effective in reducing panic symptoms, but sertraline was better tolerated. Imagine a desert traveler facing a challenging journey, with two paths leading to their destination. Sertraline and paroxetine represent these paths, each offering potential benefits, but with distinct characteristics that influence the traveler's experience. This study suggests that sertraline could be a preferable path for individuals seeking relief from panic disorder.

Panic Disorder: Finding Relief in the Sands of Anxiety

Panic disorder can be a debilitating condition, characterized by intense fear and anxiety that can significantly impact daily life. This study provides valuable insights into the effectiveness of two commonly prescribed medications, highlighting the importance of considering individual patient needs and preferences when choosing a treatment approach. The journey of managing panic disorder is like traversing a vast and unpredictable desert, but with the right guidance and support, individuals can find pathways towards relief and well-being.

Dr.Camel's Conclusion

This study compares the efficacy and tolerability of sertraline and paroxetine in the treatment of panic disorder. While both medications are effective, sertraline demonstrates better tolerability and less clinical worsening during taper. The quest for effective and well-tolerated treatments for panic disorder is like a continuous exploration of a vast and complex desert, where researchers and clinicians strive to find new pathways towards alleviating anxiety and promoting recovery.

Date :
  1. Date Completed 2004-05-20
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

15096081

DOI: Digital Object Identifier

10.4088/jcp.v65n0317

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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