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ABVD plus subtotal nodal versus involved-field radiotherapy in early-stage Hodgkin's disease: long-term results.

Author: BonadonnaGianni, BonfanteValeria, Di RussoAnna, ValagussaPinuccia, VillaniFabrizio, VivianiSimonetta

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

While radiation therapy (RT) alone can cure a significant proportion of patients with early-stage Hodgkin's disease, combined-modality approaches have improved outcomes. Further evaluation is needed to determine the optimal extent of RT fields when combined with chemotherapy.
Paper Details　
Original Abstract of the Article :
Radiation therapy (RT) alone can cure more than 80% of all patients with pathologic stage IA, IB, and IIA Hodgkin's disease, but some prognostic factors unfavorably affect treatment outcome. Combined-modality approaches improved results compared with RT, but the optimal extent of RT fields when comb...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15199092

データ提供：米国国立医学図書館（NLM）

Treating Early-Stage Hodgkin's Disease: A Balancing Act

Hodgkin's disease, a type of cancer that affects the lymphatic system, requires careful and individualized treatment strategies. This research investigates the long-term outcomes of two different treatment approaches for early-stage Hodgkin's disease: ABVD chemotherapy combined with subtotal nodal radiotherapy and ABVD chemotherapy combined with involved-field radiotherapy. The study aims to determine the effectiveness and long-term outcomes of each approach in patients with early-stage Hodgkin's disease. The study found that both treatment approaches achieved similar long-term results, demonstrating the effectiveness of ABVD chemotherapy in combination with either subtotal nodal or involved-field radiotherapy. However, the researchers noted that specific prognostic factors could influence treatment outcomes.

Navigating the Desert of Cancer Treatment: Finding the Right Path

This study underscores the importance of considering individual patient factors when determining the optimal treatment approach for early-stage Hodgkin's disease. The research highlights the effectiveness of ABVD chemotherapy combined with either subtotal nodal or involved-field radiotherapy, but emphasizes the need for personalized treatment plans based on individual patient characteristics and risk factors.

A Multifaceted Approach: Combating Hodgkin's Disease

Treating cancer requires a comprehensive and multidisciplinary approach, involving oncologists, radiation therapists, and other healthcare professionals. This study provides valuable insights into the effectiveness of different treatment approaches for early-stage Hodgkin's disease. Working closely with your doctor to develop a personalized treatment plan based on your individual needs and risk factors is crucial for achieving the best possible outcomes.

Dr. Camel's Conclusion

This study delves into the complex desert of cancer treatment, offering insights into the effectiveness of different treatment strategies for early-stage Hodgkin's disease. The research emphasizes the importance of considering individual patient factors and employing a personalized approach to ensure the best possible outcomes. As we continue to explore the vast landscape of cancer research, this study provides valuable guidance for navigating this challenging terrain and improving patient care.
Date :
  1. Date Completed 2004-09-03
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

15199092

DOI: Digital Object Identifier

JCO.2004.12.170

Related Literature

Article Analysis
・Effective treatment of radiation therapy
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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