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Effects of discontinuation as well as intervention of cyclic therapy with etidronate on bone remodeling after cementless total hip arthroplasty.
Author: FujiTakeshi, MasuharaKensaku, SeinoYoshiki, YamaguchiKatsuyuki, YamasakiSatoshi
Original Abstract of the Article :
We previously reported the effects of cyclic therapy with etidronate (CTE) on periprosthetic bone mineral density (BMD) after cementless total hip arthroplasty (THA). This study aimed to evaluate the effects of withdrawal and intervention of CTE after cementless THA. The control group consisted of 2...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15207760
データ提供:米国国立医学図書館(NLM)
Etidronate: A Bone Builder with Complex Effects
Orthopedics involves a constant search for solutions to improve bone health and repair. This study explores the use of etidronate, a bisphosphonate medication, in the context of cementless total hip arthroplasty (THA). The authors investigate the effects of both continuous and intermittent treatment with etidronate on bone remodeling after THA.
Etidronate's Influence on Bone Remodeling
The study found that continuous treatment with etidronate resulted in smaller decreases in bone mineral density (BMD) at 12 months compared to the control group, suggesting that etidronate can help preserve bone density in the early stages after THA. However, BMD decreased significantly after discontinuing etidronate, highlighting the importance of continued treatment. Intermittent etidronate treatment, starting later, led to an increase in BMD in certain areas. This suggests that etidronate can have a positive impact on bone remodeling, but it's crucial to consider the timing and duration of treatment. It's like managing a desert oasis - you need to consider the seasons and the flow of water for sustainable growth.
A Balancing Act for Bone Health
This study emphasizes the need for careful consideration of the timing, duration, and discontinuation of etidronate treatment in patients undergoing THA. It highlights the complex nature of bone remodeling and the importance of individualized approaches to managing bone health. Remember, the desert of bone health is a delicate ecosystem that requires careful attention and management.
Dr. Camel's Conclusion
This study explores the intriguing effects of etidronate on bone remodeling after THA. It underscores the importance of timing and duration of treatment, and the need for personalized approaches to optimize bone health. It's a reminder that the desert of bone health is a complex environment, and navigating it successfully requires a deep understanding of its dynamics.
Date :
- Date Completed 2005-08-19
- Date Revised 2013-11-21
Further Info :
Related Literature
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