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The effects of withdrawing tegaserod treatment in comparison with continuous treatment in irritable bowel syndrome patients with abdominal pain/discomfort, bloating and constipation: a clinical study.

Author: BardhanK D, ForbesA, MarsdenC L, MasonT, ShortG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Continuous or intermittent tegaserod treatment is less likely to result in symptom recurrence in patients with irritable bowel syndrome with constipation compared to withdrawal from treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The post-withdrawal characteristics of tegaserod treatment in patients with irritable bowel syndrome with constipation remain undefined. AIM: To evaluate the effects of continuous tegaserod treatment, versus intermittent or withdrawal of treatment in patients with irritable bowel syndro...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15233702

データ提供：米国国立医学図書館（NLM）

Tegaserod Withdrawal in Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain, bloating, and changes in bowel habits. Tegaserod is a medication used to treat IBS with constipation. This study investigated the effects of withdrawing tegaserod treatment in comparison with continuous treatment in patients with IBS. Researchers used a randomized, open-label trial, where patients were randomly assigned to either continue or stop tegaserod treatment for eight weeks. The authors compared the time it took for symptoms to return in each group.

Tegaserod: A Potential Solution for IBS Symptoms?

The study found that patients who stopped taking tegaserod experienced a faster return of symptoms than those who continued treatment. This suggests that tegaserod may be effective in controlling symptoms of IBS. A significant number of patients who continued tegaserod treatment did not experience a return of symptoms by week eight, compared to those who discontinued or used intermittent treatment. This finding has important implications for managing IBS patients and potentially improving their quality of life.

Living with IBS: What Can We Learn From This?

This study provides valuable information for understanding the role of tegaserod in IBS management. It highlights the potential benefits of continuous treatment in reducing symptom recurrence. It is important to consult a healthcare professional for proper diagnosis and treatment of IBS. While tegaserod might be beneficial for many, it is essential to consider individual needs and potential side effects.

Dr.Camel's Conclusion

This research is like a desert oasis for IBS sufferers, providing relief and hope! It sheds light on the benefits of continuous tegaserod treatment, offering a potential solution for managing IBS symptoms. It's like finding a cool spring in a scorching desert, bringing comfort and a sense of well-being.

Date :
  1. Date Completed 2004-11-01
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

15233702

DOI: Digital Object Identifier

APT2032

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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