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Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer.

Author: BrouwersMelissa, BrowmanGeorge, GersteinHertzel C, SawkaAnna M, ThabaneLehana, ThephamongkholKullathorn

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Radioactive iodine remnant ablation may reduce the risk of thyroid cancer recurrence after surgery, especially for locoregional recurrence and distant metastases, but the benefit for low-risk patients is unclear.
Paper Details　
Original Abstract of the Article :
Radioactive iodine remnant ablation destroys residual thyroid tissue after surgical resection of papillary or follicular thyroid cancer. We systematically reviewed 1543 English references to determine whether remnant ablation decreases the risk of thyroid cancer-related death or recurrence after bil...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15292285

データ提供：米国国立医学図書館（NLM）

Radioactive Iodine Remnant Ablation: A Powerful Weapon Against Thyroid Cancer?

The battle against thyroid cancer, like a desert trek, requires a multi-pronged approach. This study delves into the effectiveness of radioactive iodine remnant ablation, a treatment that targets and destroys any remaining thyroid tissue after surgery. The authors embarked on a comprehensive review of the existing literature, analyzing data from numerous studies to determine the true impact of this treatment.

Ablation's Impact on Cancer Recurrence

The study revealed that radioactive iodine remnant ablation can significantly reduce the risk of thyroid cancer recurrence, including locoregional recurrence and distant metastases. While the benefit in decreasing mortality was less consistent, the overall evidence suggests that this treatment can be a valuable tool in the fight against thyroid cancer. Think of it as a strategic alliance: ablation works together with surgery to effectively combat the spread of the disease.

Navigating the Risks and Benefits

However, the study also acknowledges that the impact of ablation may vary depending on the individual patient and the specific type of thyroid cancer. It's important to weigh the potential benefits against the risks, just as a traveler in the desert must carefully consider the challenges and rewards of each route.

Dr.Camel's Conclusion

This study provides a valuable overview of the effectiveness of radioactive iodine remnant ablation in the treatment of thyroid cancer. While further research is needed to better understand the long-term outcomes and the optimal use of this treatment, it offers a glimmer of hope for patients facing this challenging diagnosis. Just like a traveler seeking a safe path through the desert, patients and their doctors must work together to navigate the complexities of cancer treatment and choose the best course of action.

Date :
  1. Date Completed 2004-09-03
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

15292285

DOI: Digital Object Identifier

89/8/3668

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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