Systematic review of bisphosphonates for hypercalcaemia of malignancy.

Author: , BroadleyK E, EdmondsP M, PatelS, RossJ R, SaundersY

Paper Details 
Original Abstract of the Article :
BACKGROUND: Bisphosphonates are the treatment of choice for hypercalcaemia of malignancy (HCM) but there is no consensus regarding which drug or dose should be given. We designed a systematic review to investigate the efficacy of bisphosphonates in the treatment of HCM. METHODS: We identified rando...See full text at original site
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引用元:
https://doi.org/10.1191/0269216304pm914ra

データ提供:米国国立医学図書館(NLM)

Bisphosphonates for the Treatment of Hypercalcemia of Malignancy

Oh, my, hypercalcemia of malignancy, that sounds like a real camel-back breaker! It's a condition where high levels of calcium in the blood are caused by cancer. This research dives deep into the world of bisphosphonates, a group of drugs used to combat this condition. Researchers used a systematic review, a method akin to taking a long, slow journey across the desert to collect the most reliable information, to assess the effectiveness of various bisphosphonates in treating hypercalcemia of malignancy. Their findings, like a shimmering oasis in the desert, suggest that bisphosphonates are quite effective in bringing calcium levels back to normal in over 70% of patients, with minimal side effects. Of particular interest is the discovery that aminobisphosphonates are the most effective at maintaining normal calcium levels, and they should be administered in high doses regardless of the initial calcium level. This is like finding the most efficient route across a vast, scorching desert! It's exciting, as it provides a much-needed compass for medical professionals.

A Clear Path Forward for Treating Hypercalcemia of Malignancy

This study provides clear direction for treating hypercalcemia of malignancy. Bisphosphonates, particularly aminobisphosphonates in high doses, are a promising therapeutic option. This information is crucial for doctors to effectively manage this complex condition.

Hope for Patients with Hypercalcemia of Malignancy

This research offers a glimmer of hope for patients with hypercalcemia of malignancy. The effectiveness of bisphosphonates provides a better understanding of this condition and offers a clear path forward for treatment, bringing a much-needed sense of calm amidst the storms of a cancer diagnosis. This discovery is like finding a cool, refreshing spring in the heart of the desert.

Dr.Camel's Conclusion

This research is a true camel-back-breaker, a groundbreaking discovery in the treatment of hypercalcemia of malignancy. It's a roadmap, a compass, and a source of hope for both patients and doctors. The desert of this complex condition is now much easier to navigate thanks to this insightful research. This research is a true testament to the power of scientific inquiry, a testament to the resilience and determination of those who seek to improve the lives of others.

Date :
  1. Date Completed 2004-11-02
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

15332420

DOI: Digital Object Identifier

10.1191/0269216304pm914ra

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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