Paper Details

  1. Home
  2. Paper Details

Randomized, placebo-controlled comparison of early use of frovatriptan in a migraine attack versus dosing after the headache has become moderate or severe.

Author: CadyRoger, ElkindArthur, GoldsteinJerome, KeywoodCharlotte

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Early use of frovatriptan for migraine attacks was found to be more effective than later use, resulting in a higher, earlier, and sustained pain-free response. It also prevented headache progression and reduced pain burden and functional disability.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate whether frovatriptan would provide greater relief if given early during a migraine attack. RESEARCH DESIGN AND METHODS: Adults with a history of migraine of at least 1 year, and who had 2-8 headaches in the previous month were recruited from 19 US centres for a prospective, p...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1185/030079904x2745

データ提供：米国国立医学図書館（NLM）

Frovatriptan for Migraine: Early Treatment for Greater Relief

The field of [migraine treatment] continues to evolve, with researchers seeking more effective and targeted therapies. This study investigated the potential benefits of early frovatriptan administration during a migraine attack compared to delayed treatment. The authors conducted a randomized, placebo-controlled crossover study, comparing the effectiveness of early and later frovatriptan administration.

Early Frovatriptan: A Winning Strategy for Migraine

The results demonstrated that early use of frovatriptan was significantly more effective than placebo in reducing migraine pain, with a higher proportion of patients achieving pain-free status. Early treatment also reduced the need for rescue medication and prevented headache progression to moderate or severe intensity. The study suggests that early intervention with frovatriptan may be crucial for optimal migraine management.

Navigating the Migraine Landscape

Migraine is a debilitating condition that can significantly impact quality of life. This study provides evidence that early treatment with frovatriptan may offer significant benefits for migraine sufferers. It's essential for individuals with migraine to work closely with their healthcare providers to develop a personalized management plan that incorporates strategies for early intervention and prevention. Just as a camel adapts to the changing conditions of the desert, migraine sufferers can learn to manage their condition effectively with appropriate treatment and preventative measures.

Dr.Camel's Conclusion

This study adds to the growing body of evidence suggesting the potential benefits of early treatment for migraine. The findings highlight the importance of addressing migraine symptoms promptly to maximize the effectiveness of treatment and improve patient outcomes. Just as a camel must anticipate the challenges of the desert, migraine sufferers can learn to anticipate their headaches and take proactive steps to manage their condition.

Date :
  1. Date Completed 2005-01-26
  2. Date Revised 2019-09-11
Further Info :

Pubmed ID

15383196

DOI: Digital Object Identifier

10.1185/030079904x2745

Related Literature

Article Analysis
・Effects of frovatriptan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.