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Treatment of anorexia and malnutrition in peritoneal dialysis patients with megestrol acetate.

Author: AguileraAbelardo, BajoM Auxiliadora, CosteroOlga, GilFernando, HeviaCovadonga, RosSilvia, SelgasRafael, del PesoGloria

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Megestrol acetate (MA) is a drug that can increase appetite and weight. This study found that MA was effective in improving appetite, increasing serum albumin levels, and increasing weight in PD patients. No side effects were observed.
Paper Details　
Original Abstract of the Article :
Anorexia and malnutrition are common complications and powerful predictors of morbidity and mortality in peritoneal dialysis (PD) patients. Megestrol acetate (MA) is a progestogen that has been demonstrated to increase appetite and weight in patients with cancer or acquired immunodeficiency syndrome...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15384828

データ提供：米国国立医学図書館（NLM）

Megestrol Acetate: A Potential Treatment for Anorexia and Malnutrition in Peritoneal Dialysis Patients

Peritoneal dialysis (PD) is a common treatment for kidney failure, but it can lead to complications like anorexia and malnutrition, which significantly impact patient health and survival. Megestrol acetate (MA) is a drug that has shown promise in stimulating appetite and promoting weight gain in patients with cancer and HIV/AIDS. This study investigates the potential benefits of MA in treating anorexia and malnutrition in PD patients.

Megestrol Acetate: A Potential Solution for Anorexia and Malnutrition in PD Patients

This study found that MA significantly improved appetite and weight in the majority of PD patients. While serum albumin levels showed a nonsignificant increase, the study suggests that MA could be a valuable tool for managing malnutrition in PD patients. The study also highlights the absence of significant side effects, further supporting the potential benefits of MA therapy. This study offers hope for PD patients struggling with anorexia and malnutrition, suggesting that MA could play a crucial role in improving their overall health and well-being.

Addressing Malnutrition in Peritoneal Dialysis Patients: A Multifaceted Approach

The study emphasizes the importance of addressing the complex issue of malnutrition in PD patients. The findings suggest that MA could be an effective treatment option, but it's crucial to recognize that malnutrition is a multifaceted problem requiring a comprehensive approach. This study encourages patients and physicians to work together to develop individualized treatment plans that address the underlying causes of malnutrition and optimize patient outcomes.

Dr. Camel's Conclusion

This study explores the potential of MA to combat malnutrition in PD patients, highlighting its ability to stimulate appetite and promote weight gain. Like a camel adapting to the harsh desert environment, PD patients require tailored strategies to manage their health challenges. This study underscores the importance of a multidisciplinary approach to address malnutrition, ensuring the best possible care for individuals with kidney failure.

Date :
  1. Date Completed 2004-11-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15384828

DOI: Digital Object Identifier

15384828

Related Literature

Article Analysis
・Side Effects of megestrol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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