Effects of antiemetic drugs on glucose 6-phosphate dehydrogenase and some antioxidant enzymes.

Author: KüfreviogluO Irfan, OzmenIsmail

Paper Details 
Original Abstract of the Article :
The aim of this study was to investigate effect of antiemetics on G6PD and antioxidant enzymes. Antiemetics are currently being used to reduce or prevent nausea and vomiting in patients. This is the first study to show effect of antiemetics on glucose-6-phosphate dehydrogenase (G6PD) and antioxidant...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15458770

データ提供:米国国立医学図書館(NLM)

Antiemetics and Oxidative Stress

The field of [pharmacology] is constantly evaluating the [impact of medications] on [various bodily processes]. This study investigates the [effects of antiemetic drugs] on [glucose 6-phosphate dehydrogenase (G6PD)] and [antioxidant enzymes]. The authors discovered that [certain antiemetics] can significantly [inhibit G6PD activity] and alter the activity of [other antioxidant enzymes], highlighting the potential [oxidative stress] associated with [antiemetic use]. This research provides important information for [healthcare providers] and [patients] considering the use of [antiemetics].

Antiemetics and Oxidative Stress: A Potential Concern

This study found that [antiemetics] can have a [significant impact] on [G6PD and antioxidant enzymes], potentially leading to [oxidative stress]. The authors suggest that [further research] is needed to understand the [long-term implications] of these findings.

Understanding the Potential Risks of Antiemetics

This research emphasizes the importance of [considering the potential risks] associated with [antiemetic use]. It highlights the need for [careful monitoring] and [appropriate patient selection] when [prescribing antiemetics], especially in individuals with [preexisting conditions] or [increased susceptibility] to [oxidative stress].

Dr.Camel's Conclusion

Antiemetics, like a cool desert breeze, can offer relief from nausea and vomiting. However, this research suggests that they may also have [unintended consequences] for [oxidative stress]. It reminds us that even seemingly benign medications can have [complex effects] on our bodies, underscoring the importance of [carefully weighing the risks and benefits] of any treatment.

Date :
  1. Date Completed 2005-02-25
  2. Date Revised 2015-08-31
Further Info :

Pubmed ID

15458770

DOI: Digital Object Identifier

S1043661804001392

Related Literature

SNS
PICO Info
in preparation
Languages

English

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