Neridronate prevents bone loss in patients receiving androgen deprivation therapy for prostate cancer.

Author: AnastasiGiuseppina, AtteritanoMarco, CatalanoAntonino, FrisinaNicola, GaudioAgostino, LascoAntonino, MelloniDarwin, MorabitoNancy, TrifilettiAldo

Overview

Paper Details 
Original Abstract of the Article :
UNLABELLED: Today, androgen deprivation therapy is a cornerstone of treatment for advanced prostate cancer, although it presents important complications such as osteoporosis. Neridronate, a relatively new bisphosphonate, is able to prevent bone loss in patients with prostate cancer during androgen a...See full text at original site
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引用元:
https://doi.org/10.1359/JBMR.040813

データ提供:米国国立医学図書館(NLM)

Protecting Bones in a Stormy Desert

The world of prostate cancer treatment is a vast and often turbulent desert, where treatments like androgen deprivation therapy (ADT) can lead to unforeseen consequences like osteoporosis. This research delves into a promising oasis, exploring the use of neridronate, a bisphosphonate, to prevent bone loss in men undergoing ADT.

Nerisdronate: A Shelter in the Desert

The study found that neridronate was effective in preventing bone loss in the hip and lumbar spine in men receiving ADT. This is like creating a sturdy shelter in the desert, protecting the bones from the harsh effects of ADT. The researchers compared two groups: one receiving calcium and cholecalciferol (vitamin D) supplements and another receiving the same supplements plus neridronate. The group with neridronate experienced significantly less bone loss, indicating the effectiveness of this treatment.

A Safe Haven in the Desert

The researchers observed no significant side effects from neridronate treatment, making it a potentially safe and effective option for men with prostate cancer undergoing ADT. This finding is like discovering a hidden oasis, offering respite from the challenges of prostate cancer treatment.

Dr. Camel's Conclusion

This research provides a hopeful glimpse of a potential solution to the bone loss associated with ADT for prostate cancer. Neridronate emerges as a potential oasis, offering a safe and effective way to protect bones in the harsh desert of cancer treatment.

Date :
  1. Date Completed 2005-03-24
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

15476575

DOI: Digital Object Identifier

10.1359/JBMR.040813

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PICO Info
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Languages

English

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