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Fatal fat embolism following amphotericin B lipid complex injection.
Author: FrenchSamuel W, TolentinoLucilene F, TsaiSteve F, WittMallory D
Original Abstract of the Article :
A case of amphotericin B lipid complex induced fatal fat embolism is described. A 41-year-old Caucasian man with AIDS was undergoing treatment for cryptococcal meningitis with amphotericin B. His course was complicated by renal failure necessitating a change in therapy to amphotericin B lipid comple...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.yexmp.2004.07.001
データ提供:米国国立医学図書館(NLM)
A Rare Case of Fatal Fat Embolism: A Desert Storm in the Body
Amphotericin B lipid complex (Abelcet) is a powerful antifungal medication that can be a real desert storm for patients. While effective in treating fungal infections, it has been associated with rare but serious side effects, including fatal fat embolism. This case report describes a fatal fat embolism that occurred after administration of amphotericin B lipid complex to a 41-year-old man with AIDS. The study analyzes the patient's clinical presentation and autopsy findings, highlighting the potential for this rare complication.
Fatal Fat Embolism: A Rare but Serious Complication
This case report serves as a stark reminder of the potential for serious complications associated with amphotericin B lipid complex. It underscores the importance of careful monitoring and early detection of symptoms. The study highlights the need for further research to understand the mechanisms underlying this rare complication and to develop strategies for prevention and early intervention.
Implications for Clinical Practice
This case report provides valuable insights for clinicians treating patients with fungal infections. It emphasizes the importance of being vigilant for signs and symptoms of fat embolism, especially in patients receiving amphotericin B lipid complex. Early detection and intervention are crucial for improving patient outcomes and preventing potentially life-threatening complications.
Dr.Camel's Conclusion
This case report serves as a cautionary tale, highlighting the hidden dangers that can lurk within even the most effective medications. The occurrence of fatal fat embolism after amphotericin B lipid complex administration is a rare but serious complication. It's important to be aware of this potential risk and to monitor patients closely for any signs or symptoms.
Date :
- Date Completed 2004-12-14
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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