Simultaneous administration of vardenafil and tamsulosin does not induce clinically significant hypotension in patients with benign prostatic hyperplasia.

Author: AuerbachStephen M, CihonFrank, GittelmanMarc, MazzuArthur, SundaresanPavur, WhiteWilliam B

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To assess the pharmacodynamic effects of coadministered vardenafil and tamsulosin in patients with benign prostatic hyperplasia (BPH) undergoing stable tamsulosin therapy. METHODS: In this Phase 1, placebo-controlled, two-stage, two-way, crossover study, 22 patients undergoing stable (l...See full text at original site
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引用元:
https://doi.org/10.1016/j.urology.2004.07.038

データ提供:米国国立医学図書館(NLM)

Exploring the Safety of Vardenafil and Tamsulosin Combination

In the vast desert of pharmaceutical research, researchers are constantly searching for safe and effective combinations of medications. This study explores the potential interaction between vardenafil and tamsulosin, two medications commonly used to treat benign prostatic hyperplasia (BPH). The study aimed to investigate whether the combination of these drugs induces clinically significant hypotension, a potential concern when administering medications that affect blood pressure. The researchers conducted a placebo-controlled, crossover study to assess the effects of coadministering these medications in patients with BPH.

A Safe Combination for BPH Management

The results of the study showed that [研究結果]. This finding suggests that [社会的な意義] and provides reassurance for patients and clinicians.

Navigating the Treatment of BPH

This study offers valuable information for patients and clinicians managing BPH. The research found that [研究結果]. While the study found the combination to be safe, individuals should always consult their healthcare providers for personalized guidance and to address any concerns about potential drug interactions.

Dr.Camel's Conclusion

This study, like a refreshing oasis in the arid landscape of pharmaceutical research, provides evidence for the safety of coadministering vardenafil and tamsulosin in patients with BPH. This finding is crucial for ensuring patient safety and optimizing treatment outcomes. However, further research is needed to explore the long-term effects of this combination therapy and to investigate its potential benefits for different patient populations.
Date :
  1. Date Completed 2005-11-14
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15533493

DOI: Digital Object Identifier

10.1016/j.urology.2004.07.038

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