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Risperidone plasma levels, clinical response and side-effects.

Author: MöllerH J, MüllerN, Müller-ArendsA, RiedelMichael, SchwarzM J, SpellmannI, StrassnigM, WeberK, ZachJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the relationship between risperidone dose, serum drug levels, and clinical response in patients with schizophrenia. The study also examined the influence of genetic factors on risperidone metabolism.
Paper Details　
Original Abstract of the Article :
Assessment of the relation between oral risperidone dose, serum drug levels and clinical response may provide important information for rational treatment decisions. Inter-individual differences in the liver cytochrome P450 system, especially in the CYP2D6 subsystem, which account for a significant ...See full text at original site
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引用元：
https://doi.org/10.1007/s00406-004-0556-4

データ提供：米国国立医学図書館（NLM）

Risperidone Plasma Levels, Clinical Response, and Side Effects

This study, like a camel navigating the intricate pathways of the human body, explored the relationship between risperidone dosage, blood levels, clinical response, and side effects in patients receiving this antipsychotic medication. The researchers investigated the role of genetic variations in the liver enzyme CYP2D6, which is involved in metabolizing risperidone, in influencing drug levels and clinical outcomes.

Decoding the Desert of Risperidone Metabolism

This study, like a seasoned traveler uncovering the secrets of a vast desert, delved into the complexities of risperidone metabolism. The researchers discovered that genetic variations in CYP2D6, like variations in the desert's terrain, can significantly affect drug levels and response to treatment.

Navigating the Desert of Individual Differences

This study, like a camel adapting to the unique challenges of each desert region, emphasizes the importance of individualizing treatment approaches to account for genetic differences and their impact on medication metabolism and response. The findings highlight the need for personalized medicine strategies in optimizing treatment outcomes and minimizing adverse effects.

Dr. Camel's Conclusion

This study, like a camel leaving its mark on the shifting sands of knowledge, underscores the importance of understanding individual differences in drug metabolism and response. It emphasizes the need for personalized treatment approaches that consider genetic variations and patient-specific factors to optimize therapeutic outcomes.
Date :
  1. Date Completed 2005-11-30
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

15565299

DOI: Digital Object Identifier

10.1007/s00406-004-0556-4

Related Literature

Article Analysis
・Side Effects of risperidone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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