[Magnesium sulfate in obstetrics: current data].

Author: AzriaE, CabrolD, GoffinetF, KayemG, MignonA, TsatsarisV

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To review the available evidence regarding history, pharmacology, physiology, maternal/fetal side effects, and efficacy of magnesium sulfate in pregnant women. DATA SOURCES: The literature in Medline was searched from 1966 through April 2003 using the terms "magnesium sulfate," "tocolyti...See full text at original site
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引用元:
https://doi.org/10.1016/s0368-2315(04)96564-7

データ提供:米国国立医学図書館(NLM)

Magnesium Sulfate: A Versatile Tool in Obstetrics

Magnesium sulfate is a widely used medication in obstetrics, but its exact role and effectiveness are still being debated. This comprehensive review examines the history, pharmacology, and efficacy of magnesium sulfate in pregnant women, specifically addressing its use in preventing preterm delivery and eclampsia.

The authors summarize the current evidence on magnesium sulfate's use in both preventing preterm delivery (tocolytic effect) and eclampsia (neuroprotective effect). While randomized controlled trials and systematic reviews have confirmed magnesium sulfate's efficacy in preventing eclampsia, its use as a tocolytic remains controversial. The review explores the benefits and risks of using magnesium sulfate for both severe and mild preeclampsia, highlighting the need for careful consideration and evidence-based decision-making.

Magnesium Sulfate: A Complex and Controversial Tool

This comprehensive review provides valuable insights into the use of magnesium sulfate in obstetrics. While its efficacy in preventing eclampsia is established, its role as a tocolytic is still under scrutiny. The review suggests that high cumulative doses may be associated with increased infant mortality, emphasizing the need for careful monitoring and dose optimization. It also highlights the importance of weighing the potential benefits and risks of magnesium sulfate treatment in different clinical scenarios.

Navigating the Use of Magnesium Sulfate

The use of magnesium sulfate in obstetrics is a complex and nuanced issue. It's crucial to understand the potential benefits and risks associated with its use and to make informed decisions based on the specific clinical context. The review highlights the importance of evidence-based medicine in guiding clinical practice and ensures that the use of magnesium sulfate is optimized for patient safety and well-being. It's crucial to discuss your concerns and options with your healthcare provider to determine the best approach for managing your pregnancy.

Dr.Camel's Conclusion

Magnesium sulfate is a valuable tool in the obstetrician's toolkit, but its use requires careful consideration. It's like navigating a vast desert, where understanding the terrain and choosing the right path is crucial for a safe and successful journey. This review provides a comprehensive overview of the evidence, guiding us towards informed decision-making and ensuring the best possible outcomes for both mother and child.

Date :
  1. Date Completed 2005-04-12
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

15567967

DOI: Digital Object Identifier

10.1016/s0368-2315(04)96564-7

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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