Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study.

Author: DrapersJ A G, Felt-BersmaR J F, HansenB E, KuipersE J, WestR L, van TilburgA J P, van der WoudeC J

Paper Details 
Original Abstract of the Article :
BACKGROUND: Ciprofloxacin is effective in perianal Crohn's disease but after treatment discontinuation symptoms reoccur. Infliximab is effective but requires maintenance therapy. AIM: To evaluate the effect of combined ciprofloxacin and infliximab in perianal Crohn's disease. METHODS: A double-bli...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2004.02247.x

データ提供:米国国立医学図書館(NLM)

The Desert of Crohn's Disease: Seeking Relief for Perianal Fistulae

The desert of Crohn's disease can be a harsh and unforgiving place, particularly when it comes to perianal fistulae, which can cause significant pain and discomfort. This study investigates the potential benefits of combining ciprofloxacin, an antibiotic, with infliximab, a biologic therapy, in treating perianal fistulae in patients with Crohn's disease.

Navigating the Desert: A Combined Approach to Treatment

The researchers conducted a double-blind, placebo-controlled study, comparing the effectiveness of ciprofloxacin plus infliximab to infliximab alone. The results showed that patients treated with the combination of ciprofloxacin and infliximab tended to have a better clinical response, with a greater reduction in the number of draining fistulae.

Finding Oasis in the Desert: Hope for Perianal Fistulae

This study suggests that combining ciprofloxacin with infliximab may offer a more effective treatment option for perianal fistulae in patients with Crohn's disease. It highlights the potential benefits of a multi-pronged approach to managing complex inflammatory conditions. As we journey through the desert of Crohn's disease, let's embrace the hope that innovative treatments can help us to find relief and achieve a better quality of life.

Dr.Camel's Conclusion

The desert of Crohn's disease can be a difficult journey. This study provides hope that a combination of therapies may offer a more effective way to navigate the challenges of perianal fistulae. Like a camel seeking water in a harsh desert, let's remain optimistic and explore the potential of new and innovative treatments. Remember, there is always a possibility of finding a source of relief and healing in the desert of Crohn's disease.

Date :
  1. Date Completed 2005-06-03
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

15606395

DOI: Digital Object Identifier

10.1111/j.1365-2036.2004.02247.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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