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Infliximab in the treatment of steroid-dependent ulcerative colitis.

Author: ArmuzziA, De PascalisB, FedeliP, GasbarriniA, GasbarriniG, LeoD, LupascuA, MelinaD, MentellaM C, PolaP, VincentiF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Infliximab appears to be as effective as steroids in the management of moderate to severe steroid-dependent ulcerative colitis.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND OBJECTIVES: Infliximab has proven efficacious in the treatment of Crohn's disease. Limited and contrasting data are available on effectiveness of anti-TNF alpha therapy in ulcerative colitis. We evaluated the efficacy of infliximab in the management of steroid-dependent ulcerative col...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15638236

データ提供：米国国立医学図書館（NLM）

Infliximab in the Treatment of Steroid-Dependent Ulcerative Colitis

Ulcerative colitis (UC), a chronic inflammatory bowel disease, often requires long-term treatment and management. This research explores the effectiveness of infliximab, a medication that blocks the action of TNF-alpha, in treating steroid-dependent UC. The study, a randomized controlled trial, compared infliximab to methylprednisolone in inducing and maintaining remission in patients with moderate to severe steroid-dependent UC. The findings suggest that infliximab is as effective as steroids in achieving remission and potentially offers a viable alternative for managing steroid-dependent UC, providing a potentially safer and more effective long-term treatment option.

A New Path Through the Desert of Ulcerative Colitis

This research, like a new caravan route across the vast desert of UC treatment, explores the potential of infliximab as a viable alternative to steroids. The findings, similar to a well-stocked oasis discovered in the desert, offer hope for a more effective and potentially safer treatment option for patients with steroid-dependent UC.

Navigating the Challenges of Ulcerative Colitis Treatment: Infliximab

Imagine a desert traveler seeking a more sustainable way to journey through the harsh landscape. Infliximab, like a sturdy camel adapted to the desert environment, offers a potential solution for individuals struggling with steroid-dependent UC. This research provides valuable information about the effectiveness and safety of infliximab, offering a new path towards long-term remission and improved quality of life for patients with UC.

Dr. Camel's Conclusion

This research, like a caravan traversing the desert of UC treatment, explores the potential of infliximab as a promising alternative to steroids. The findings suggest that infliximab offers a potentially safer and more effective long-term treatment option, offering hope for improved outcomes for individuals living with UC.

Date :
  1. Date Completed 2005-02-04
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

15638236

DOI: Digital Object Identifier

15638236

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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