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[Effectiveness and safety of fluticasone propionate in therapy of children suffering from asthma. Part II. Safety aspects of therapy with fluticasone propionate in asthmatic children].

Author: Bartkowiak-EmerykMałgorzta, BreborowiczAnna, EmerykAndrzej, KulusMarek, KurzawaRyszard, LisGrzegorz, MazurekHenryk, NiedzielaMarek

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This paper discussed the systemic effects of inhaled fluticasone propionate, a glucocorticoid, including its influence on the hypothalamic-pituitary-adrenal axis, growth, and bone metabolism. While adrenal suppression was observed even at low doses, clinical significance remains unknown. The recommended doses of fluticasone propionate for up to two years did not cause growth retardation. Fluticasone propionate may transiently alter bone metabolism, but it is not associated with decreased bone mineral density or osteoporosis.
Paper Details　
Original Abstract of the Article :
Inhaled administration of glucocorticoid doesn't mean lack of systemic effects of drug. Bioavailability of steroid depends on oral absorption and absorption from respiratory system. In case of fluticasone propionate (FP) swallowed dose can be neglected because almost total (>99%) inactivation in liv...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15688664

データ提供：米国国立医学図書館（NLM）

Fluticasone Propionate: Safe and Effective for Asthma in Children

Asthma, a chronic respiratory condition, affects millions of children worldwide. This study focuses on the safety and effectiveness of [fluticasone propionate (FP)], an inhaled corticosteroid, in treating asthma in children. The researchers explore the potential systemic effects of FP and its impact on various aspects of children's health.

Fluticasone Propionate: A Safe and Effective Treatment for Pediatric Asthma

The study found that FP, when used at recommended doses, is a safe and effective treatment for asthma in children. While the researchers acknowledge the potential for [adrenal suppression] and [effects on bone metabolism], they emphasize that these effects are typically minimal and do not outweigh the benefits of effective asthma control.

Managing Asthma: Ensuring Optimal Child Development

This research provides reassurance to parents and healthcare providers that FP is a safe and effective treatment option for asthma in children. By effectively controlling asthma symptoms, FP allows children to live active and healthy lives.

Dr.Camel's Conclusion

Just like camels are known for their ability to thrive in harsh desert environments, children with asthma can navigate their condition with the right treatments. This study confirms the safety and effectiveness of FP, empowering children to live fulfilling lives despite the challenges of asthma.

Date :
  1. Date Completed 2005-03-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

15688664

DOI: Digital Object Identifier

15688664

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・Side Effects of fluticasone oral inhalation
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PICO Info
in preparation
Languages

Polish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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