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Bulking agents, antispasmodic and antidepressant medication for the treatment of irritable bowel syndrome.

Author: Meineche-SchmidtV, MurisJ, QuarteroA O, RubinG, de WitN

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

There is weak evidence for the efficacy of drug therapies for irritable bowel syndrome (IBS). Antispasmodic drugs may improve abdominal pain and global assessment of symptoms, but it is unclear whether anti-spasmodic subgroups are individually effective. There is no clear evidence of benefit for antidepressants or bulking agents.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Irritable bowel syndrome (IBS) is a common health problem, often presenting in primary care as well as in internal medicine and gastroenterology outpatient clinics. Therapeutic options are dominated by drug therapies but there is uncertainty about their effectiveness. OBJECTIVES: The pr...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD003460.pub2

データ提供：米国国立医学図書館（NLM）

Irritable Bowel Syndrome: Exploring Treatment Options

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that can significantly impact quality of life. This extensive review delves into the efficacy of various drug therapies for IBS, including bulking agents, antispasmodics, and antidepressants. The authors systematically analyzed a large number of randomized controlled trials to assess the effectiveness of these medications in managing IBS symptoms. The results highlight the importance of personalized care and the need for further research to optimize treatment strategies.

Evaluating Drug Therapies for Irritable Bowel Syndrome

The researchers found limited evidence for the efficacy of drug therapies for IBS. While antispasmodic drugs showed some benefit in reducing abdominal pain and improving global symptom assessment, the individual effectiveness of specific antispasmodic subgroups remains unclear. The review found no clear evidence of benefit for antidepressants or bulking agents.

Personalized Care for Irritable Bowel Syndrome

The study emphasizes the importance of personalized care for IBS, acknowledging that each individual experiences symptoms differently. It highlights the need for careful consideration of individual symptoms and preferences when selecting treatment options. Just as different travelers might seek different refreshments in a desert oasis, individuals with IBS may require tailored approaches to manage their condition effectively.

Dr. Camel's Conclusion

This comprehensive review underscores the complexities of treating irritable bowel syndrome. The desert of IBS symptoms can be vast and varied, requiring careful navigation and tailored solutions. The researchers highlight the importance of personalized care and the need for further research to develop more effective treatments. It's a reminder that the pursuit of optimal health is an ongoing journey, requiring both perseverance and flexibility.

Date :
  1. Date Completed 2005-07-19
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

15846668

DOI: Digital Object Identifier

10.1002/14651858.CD003460.pub2

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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