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Impact of nonsteroidal antiinflammatory drugs on the cardioprotective effects of aspirin.

Author: AnsaniNicole T, CormanShelby L, FedutesBethany A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Pharmacodynamic data indicating an interaction between aspirin and NSAIDs have not translated to a consistent clinical effect in observational studies. In the absence of a randomized, controlled, clinical outcomes study, there is insufficient evidence to dictate a change in therapy.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To examine the evidence of a pharmacodynamic interaction between aspirin and nonsteroidal antiinflammatory drugs (NSAIDs); specifically, to determine whether a deleterious relationship exists with respect to the cardioprotective effects of aspirin. DATA SOURCES: Primary articles were ide...See full text at original site
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引用元：
https://doi.org/10.1345/aph.1E514

データ提供：米国国立医学図書館（NLM）

Aspirin and NSAIDs: Navigating the Interplay of Medications

The field of cardiology is constantly seeking to understand the complex interactions between different medications. This review examines the potential interaction between aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) with respect to the cardioprotective effects of aspirin. The authors reviewed available research, finding that while some studies indicate a potential pharmacodynamic interaction between aspirin and certain NSAIDs, there is insufficient evidence to definitively conclude that this interaction affects clinical outcomes. This review highlights the need for further research to clarify the relationship between aspirin and NSAID use, particularly with respect to cardiovascular health.

Understanding the Shifting Sands of Medication Interactions

This research underscores the importance of understanding the complex interactions between different medications. It is crucial to consider the potential impact of these interactions on patient health and to make informed decisions about medication use.

Protecting Cardiovascular Health

This research emphasizes the importance of open communication between patients and their healthcare providers regarding medication use. Patients should discuss any concerns they have about potential drug interactions with their healthcare provider to ensure they receive safe and effective treatment.

Dr.Camel's Conclusion

This research is like navigating a desert filled with hidden sandstorms, reminding us of the importance of understanding medication interactions. By carefully considering the potential interplay of different medications, we can ensure safer and more effective treatments for cardiovascular health.

Date :
  1. Date Completed 2006-03-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15870140

DOI: Digital Object Identifier

10.1345/aph.1E514

Related Literature

Article Analysis
・Effects of aspirin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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