As-needed inhaled beta2-adrenoceptor agonists in moderate-to-severe asthma: current recommendations.

Author: CockcroftDonald W

Paper Details 
Original Abstract of the Article :
Intermediate-acting inhaled beta2-agonists (e.g. albuterol [salbutamol]), once recommended for round-the-clock bronchodilation, are now recommended to be used exclusively as-needed. Guidelines advise that asthma should be controlled with anti-inflammatory therapeutic strategies so that the as-needed...See full text at original site
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引用元:
https://doi.org/10.2165/00151829-200504030-00002

データ提供:米国国立医学図書館(NLM)

Understanding the Role of Inhaled Beta2-Adrenoceptor Agonists in Asthma Management

Asthma, a chronic inflammatory lung disease, affects millions worldwide. Effective management of asthma requires a multi-pronged approach, often including inhaled corticosteroids (ICS) and inhaled beta2-adrenoceptor agonists (beta2-agonists). This review delves into the evolving role of beta2-agonists, specifically focusing on their as-needed use in patients with moderate-to-severe asthma.

The review emphasizes the shift from regular scheduled use to as-needed use of beta2-agonists. This shift stems from the recognition that asthma is primarily an inflammatory condition, and ICS are essential for long-term control. While beta2-agonists effectively relieve symptoms, their frequent use can lead to tolerance, increased airway responsiveness, and overreliance on symptom relief, potentially hindering asthma control.

The review analyzes the evidence supporting the as-needed, infrequent use of beta2-agonists, highlighting their role as a marker of asthma control. It underscores the importance of adopting a comprehensive approach to asthma management, prioritizing ICS and environmental control while utilizing beta2-agonists as needed for symptom relief.

The Importance of Asthma Control: A Balancing Act

This review sheds light on the delicate balance between symptom relief and long-term asthma control. While beta2-agonists effectively address immediate symptoms, their frequent use can have unintended consequences. The key lies in maintaining adequate asthma control through consistent use of ICS and other anti-inflammatory therapies, while utilizing beta2-agonists as needed.

Navigating the Desert of Asthma Management

Asthma management is a journey, not a destination. Like a camel navigating the vast desert, those with asthma must be adaptable and vigilant in their approach to managing their condition. By understanding the evolving role of beta2-agonists and embracing a comprehensive approach, individuals can navigate the complexities of asthma management and achieve optimal lung health.

Dr.Camel's Conclusion

This review emphasizes the shift from regular scheduled use to as-needed use of inhaled beta2-agonists for asthma management. It emphasizes the importance of a comprehensive approach that prioritizes long-term control with anti-inflammatory therapies while utilizing beta2-agonists as needed for symptom relief.

Date :
  1. Date Completed 2005-10-06
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

15987233

DOI: Digital Object Identifier

10.2165/00151829-200504030-00002

Related Literature

SNS
PICO Info
in preparation
Languages

English

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