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As-needed inhaled beta2-adrenoceptor agonists in moderate-to-severe asthma: current recommendations.
Author: CockcroftDonald W
Original Abstract of the Article :
Intermediate-acting inhaled beta2-agonists (e.g. albuterol [salbutamol]), once recommended for round-the-clock bronchodilation, are now recommended to be used exclusively as-needed. Guidelines advise that asthma should be controlled with anti-inflammatory therapeutic strategies so that the as-needed...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2165/00151829-200504030-00002
データ提供:米国国立医学図書館(NLM)
Understanding the Role of Inhaled Beta2-Adrenoceptor Agonists in Asthma Management
Asthma, a chronic inflammatory lung disease, affects millions worldwide. Effective management of asthma requires a multi-pronged approach, often including inhaled corticosteroids (ICS) and inhaled beta2-adrenoceptor agonists (beta2-agonists). This review delves into the evolving role of beta2-agonists, specifically focusing on their as-needed use in patients with moderate-to-severe asthma.
The review emphasizes the shift from regular scheduled use to as-needed use of beta2-agonists. This shift stems from the recognition that asthma is primarily an inflammatory condition, and ICS are essential for long-term control. While beta2-agonists effectively relieve symptoms, their frequent use can lead to tolerance, increased airway responsiveness, and overreliance on symptom relief, potentially hindering asthma control.
The review analyzes the evidence supporting the as-needed, infrequent use of beta2-agonists, highlighting their role as a marker of asthma control. It underscores the importance of adopting a comprehensive approach to asthma management, prioritizing ICS and environmental control while utilizing beta2-agonists as needed for symptom relief.
The Importance of Asthma Control: A Balancing Act
This review sheds light on the delicate balance between symptom relief and long-term asthma control. While beta2-agonists effectively address immediate symptoms, their frequent use can have unintended consequences. The key lies in maintaining adequate asthma control through consistent use of ICS and other anti-inflammatory therapies, while utilizing beta2-agonists as needed.
Navigating the Desert of Asthma Management
Asthma management is a journey, not a destination. Like a camel navigating the vast desert, those with asthma must be adaptable and vigilant in their approach to managing their condition. By understanding the evolving role of beta2-agonists and embracing a comprehensive approach, individuals can navigate the complexities of asthma management and achieve optimal lung health.
Dr.Camel's Conclusion
This review emphasizes the shift from regular scheduled use to as-needed use of inhaled beta2-agonists for asthma management. It emphasizes the importance of a comprehensive approach that prioritizes long-term control with anti-inflammatory therapies while utilizing beta2-agonists as needed for symptom relief.
Date :
- Date Completed 2005-10-06
- Date Revised 2019-11-09
Further Info :
Related Literature
English
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