A randomized placebo-controlled double-blind study of levamisole in the treatment of limited and slowly spreading vitiligo.

Author: AgarwalS, KhandpurS, PalH, PandeyR M, RamamM, SharmaV K

Paper Details 
Original Abstract of the Article :
BACKGROUND: A previous uncontrolled, open trial of levamisole in patients with limited and slowly spreading vitiligo had shown that new lesions did not develop in 94% of patients after 2-4 months of treatment with the drug. OBJECTIVES: To assess the efficacy of levamisole in the treatment of slowly...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2133.2005.06556.x

データ提供:米国国立医学図書館(NLM)

Levamisole and Vitiligo: A Double-Blind Study

This study delves into the world of vitiligo, a skin condition characterized by loss of pigmentation, and explores the potential of levamisole, a drug typically used for parasitic infections, as a treatment option. Researchers conducted a randomized double-blind trial to assess the effectiveness of levamisole in slowing the progression of vitiligo. They observed that levamisole did not significantly outperform placebo in preventing the development of new vitiligo lesions. Although a larger sample size could be needed to confirm these findings, the study provides valuable insights into the effectiveness of levamisole for vitiligo.

Levamisole's Limited Impact on Vitiligo

The research indicates that levamisole, despite its potential in previous studies, did not significantly reduce the development of new vitiligo lesions in this controlled trial. The results suggest that levamisole may not be a reliable treatment option for preventing the progression of vitiligo.

Navigating Vitiligo: What Does This Mean for You?

This research underlines the importance of seeking individualized treatment options for vitiligo. While levamisole might not be the answer for everyone, other treatment modalities like topical medications and light therapy have shown promise. It is vital to consult a dermatologist for a comprehensive evaluation and personalized treatment plan.

Dr.Camel's Conclusion

Like a camel navigating a shifting sand dune, understanding vitiligo requires ongoing research and evaluation of various treatment options. This study highlights the importance of double-blind trials in objectively assessing the effectiveness of potential treatments. The results, while not entirely conclusive, provide valuable insights into the role of levamisole in managing vitiligo.

Date :
  1. Date Completed 2005-10-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16029343

DOI: Digital Object Identifier

10.1111/j.1365-2133.2005.06556.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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