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Co-dergocrine mesylate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in age-related cognitive decline.

Author: ChrispP, WadworthA N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Co-dergocrine mesylate, a combination of ergot alkaloids, has been proposed to improve cognitive function in elderly individuals with age-related cognitive decline. While some studies show a positive effect on cognitive symptoms, the clinical relevance of these findings is debated due to variability in assessment methods and lack of comparison with newer centrally active agents.
Paper Details　
Original Abstract of the Article :
Co-dergocrine mesylate is a combination of the mesylated forms of dihydroergocornine, dihydroergocristine, dihydro-alpha-ergocryptine and dihydro-beta-ergocryptine. In animal models and healthy elderly volunteers the compound improves indices of cognitive function such as memory and learning. The me...See full text at original site
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引用元：
https://doi.org/10.2165/00002512-199202030-00002

データ提供：米国国立医学図書館（NLM）

Co-dergocrine Mesylate: A Desert Remedy for Age-Related Cognitive Decline?

This study explores the potential of co-dergocrine mesylate as a treatment for age-related cognitive decline, a condition that can be as frustrating as navigating a vast desert with a faulty compass. The study examines the compound's effects on cognitive function, highlighting its potential to improve memory and learning. It's like a desert oasis that provides a boost of mental clarity and rejuvenation. However, the study also acknowledges the need for further research to determine its effectiveness and safety, as well as its place within the broader landscape of cognitive decline treatments. It's like a desert expedition, where further exploration is needed to confirm the value of this newfound oasis.

A Complex and Controversial Oasis: Co-dergocrine Mesylate

The study highlights the complexity of co-dergocrine mesylate's effects, with its potential benefits for cognitive function balanced against the need for further research. It's like an oasis surrounded by shifting sands, where its true value remains somewhat elusive.

Navigating the Desert of Age-Related Cognitive Decline

This research offers a glimpse into the potential benefits of co-dergocrine mesylate, reminding us that navigating the desert of age-related cognitive decline requires a multi-faceted approach. It's like a complex desert ecosystem, where multiple factors contribute to the overall health and resilience.

Dr.Camel's Conclusion

While co-dergocrine mesylate shows promise as a treatment for age-related cognitive decline, further research is needed to fully understand its effectiveness and safety. It's like finding a new oasis in the desert, but we need to carefully assess its resources before making it our permanent home.

Date :
  1. Date Completed 1992-07-17
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

1606351

DOI: Digital Object Identifier

10.2165/00002512-199202030-00002

Related Literature

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・Effects of ergoloid mesylates
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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