The efficacy and side effects of topiramate on refractory epilepsy in infants and young children: a multi-center clinical trial.

Author: Al AjlouniS, DaoudA S, ShormanA

Paper Details 
Original Abstract of the Article :
OBJECTIVES: This study has been conducted to assess the efficacy and safety of topiramate in refractory epilepsies in infants and young children. METHODS: A prospective clinical trial was performed in three tertiary care hospitals, on 47 children aged 6-60 months with refractory epilepsy. Topiramat...See full text at original site
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引用元:
https://doi.org/10.1016/j.seizure.2005.07.009

データ提供:米国国立医学図書館(NLM)

Topiramate for Refractory Epilepsy in Infants and Young Children

Epilepsy, a neurological condition characterized by seizures, can be particularly challenging in infants and young children. This research investigates the efficacy and safety of topiramate, an anti-epileptic drug, in treating refractory epilepsy, a form of epilepsy that doesn't respond to conventional medications. The study focused on infants and young children with epilepsy that had not responded to previous treatments.

Topiramate Shows Promise for Treating Refractory Epilepsy in Children

The study found that topiramate was effective in reducing seizure frequency in a significant proportion of children with refractory epilepsy, regardless of the specific type of epilepsy. However, the study also reported mild to moderate side effects, including drowsiness, loss of appetite, and nervousness. This highlights the importance of monitoring for potential side effects and carefully adjusting dosage based on individual needs.

Finding Hope in the Face of Epilepsy: Exploring Treatment Options for Children

This research provides valuable information for families facing the challenge of epilepsy in their children. Topiramate offers a potential treatment option for refractory epilepsy, but careful monitoring and individualized care are essential. Just as a camel protects its young in the harsh desert environment, we must strive to find the best possible care and support for children with epilepsy.

Dr. Camel's Conclusion

This research suggests that topiramate is a potentially effective treatment option for refractory epilepsy in infants and young children. While side effects should be monitored, topiramate offers hope for families seeking relief from seizures. This study underscores the importance of ongoing research to develop safe and effective treatment strategies for epilepsy in children.

Date :
  1. Date Completed 2005-12-15
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

16087357

DOI: Digital Object Identifier

10.1016/j.seizure.2005.07.009

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SNS
PICO Info
in preparation
Languages

English

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