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Comparison of pharmacological treatments for opioid-dependent adolescents: a randomized controlled trial.

Author: BadgerGary J, BickelWarren K, BrooklynJohn, MarschLisa A, QuesnelKimberly J, StangerCatherine, StothartMarne E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study found that buprenorphine, combined with behavioral interventions, is significantly more efficacious in the treatment of opioid-dependent adolescents than clonidine combined with behavioral interventions.
Paper Details　
Original Abstract of the Article :
CONTEXT: The prevalence of heroin and other opioid use has markedly increased among adolescents in the last decade; however, virtually no research has been conducted to identify effective treatments for this population. OBJECTIVE: To evaluate the relative efficacy of 2 pharmacotherapies, the partia...See full text at original site
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引用元：
https://doi.org/10.1001/archpsyc.62.10.1157

データ提供：米国国立医学図書館（NLM）

Treating Opioid Dependence in Adolescents: Buprenorphine Shows Promise

Opioid dependence, a serious public health issue, can have devastating consequences, particularly among adolescents. This study investigates the relative efficacy of two pharmacotherapies, buprenorphine hydrochloride and clonidine hydrochloride, in the detoxification of opioid-dependent adolescents. The researchers conducted a randomized controlled trial involving 36 adolescents, finding that buprenorphine was significantly more effective than clonidine in terms of treatment retention, opiate abstinence, and overall outcome.

Buprenorphine: A Beacon of Hope for Opioid-Dependent Adolescents

The study's findings suggest that buprenorphine holds significant promise for treating opioid dependence in adolescents. It's like finding a safe haven in the desert, offering refuge and support for those struggling with addiction.

Addressing Opioid Dependence: A Multidisciplinary Approach

This research highlights the critical need for comprehensive and multidisciplinary approaches to treating opioid dependence in adolescents. Combining pharmacotherapy with behavioral interventions, such as counseling and support groups, is essential for successful recovery. It's like navigating a treacherous desert - a combination of resources, knowledge, and support is vital for survival.

Dr. Camel's Conclusion

This study provides valuable insights into the treatment of opioid dependence in adolescents. Buprenorphine emerges as a promising pharmacotherapeutic option, emphasizing the importance of combining medication with behavioral interventions for optimal outcomes. Just as a wise traveler relies on both maps and guides for a successful journey through the desert, we must utilize a comprehensive approach to guide individuals towards recovery from opioid dependence.

Date :
  1. Date Completed 2005-10-24
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

16203961

DOI: Digital Object Identifier

10.1001/archpsyc.62.10.1157

Related Literature

Article Analysis
・Effective treatment of opioid use
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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