Naloxone treatment prevents prenatal stress effects on peritoneal macrophage activity in mice offspring.

Author: Carvalho-FreitasMaria Isabel R, FonsecaEvelise S M, Palermo NetoJoão, SakaiMonica

Paper Details 
Original Abstract of the Article :
The present study analyzed the effects of maternal stress (PS) and/or naloxone treatment on the activity of peritoneal macrophage in male and female Swiss mice offspring. Pregnant female rats received a daily footshock (0.2 mA) and/or a naloxone injection from gestational day 15 to 19. Experiments w...See full text at original site
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引用元:
https://doi.org/10.1159/000088759

データ提供:米国国立医学図書館(NLM)

Naloxone: A Lifeline in the Desert of Prenatal Stress

Prenatal stress can have lasting effects on offspring, creating a challenging desert environment for their development. This research, like a lifeline in a storm, investigates the potential of naloxone, an opioid antagonist, in mitigating the adverse effects of prenatal stress.

The study examines the impact of prenatal stress and naloxone treatment on the activity of peritoneal macrophages in mice offspring. The findings reveal that naloxone treatment can effectively reverse the negative effects of prenatal stress on macrophage function, suggesting a potential role for naloxone in mitigating the long-term consequences of prenatal stress.

A Protective Oasis for Offspring

The study highlights the potential of naloxone in protecting offspring from the adverse effects of prenatal stress, particularly on macrophage function. This suggests that naloxone may be a valuable tool in mitigating the long-term consequences of prenatal stress on immune system development and function.

Navigating the Desert of Prenatal Stress

This research underscores the importance of addressing the potential impact of prenatal stress on offspring development. It suggests that interventions like naloxone may hold promise in mitigating the long-term consequences of prenatal stress, promoting healthy development and well-being.

Dr. Camel's Conclusion

This study offers a compelling investigation into the potential of naloxone in mitigating the adverse effects of prenatal stress on offspring development. It highlights the importance of understanding the complex interplay between prenatal stress, opioid systems, and immune system function, paving the way for innovative strategies to protect offspring from the long-term consequences of prenatal stress.

Date :
  1. Date Completed 2006-01-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16210866

DOI: Digital Object Identifier

10.1159/000088759

Related Literature

SNS
PICO Info
in preparation
Languages

English

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