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Naloxone treatment prevents prenatal stress effects on peritoneal macrophage activity in mice offspring.
Author: Carvalho-FreitasMaria Isabel R, FonsecaEvelise S M, Palermo NetoJoão, SakaiMonica
Original Abstract of the Article :
The present study analyzed the effects of maternal stress (PS) and/or naloxone treatment on the activity of peritoneal macrophage in male and female Swiss mice offspring. Pregnant female rats received a daily footshock (0.2 mA) and/or a naloxone injection from gestational day 15 to 19. Experiments w...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000088759
データ提供:米国国立医学図書館(NLM)
Naloxone: A Lifeline in the Desert of Prenatal Stress
Prenatal stress can have lasting effects on offspring, creating a challenging desert environment for their development. This research, like a lifeline in a storm, investigates the potential of naloxone, an opioid antagonist, in mitigating the adverse effects of prenatal stress.
The study examines the impact of prenatal stress and naloxone treatment on the activity of peritoneal macrophages in mice offspring. The findings reveal that naloxone treatment can effectively reverse the negative effects of prenatal stress on macrophage function, suggesting a potential role for naloxone in mitigating the long-term consequences of prenatal stress.
A Protective Oasis for Offspring
The study highlights the potential of naloxone in protecting offspring from the adverse effects of prenatal stress, particularly on macrophage function. This suggests that naloxone may be a valuable tool in mitigating the long-term consequences of prenatal stress on immune system development and function.
Navigating the Desert of Prenatal Stress
This research underscores the importance of addressing the potential impact of prenatal stress on offspring development. It suggests that interventions like naloxone may hold promise in mitigating the long-term consequences of prenatal stress, promoting healthy development and well-being.
Dr. Camel's Conclusion
This study offers a compelling investigation into the potential of naloxone in mitigating the adverse effects of prenatal stress on offspring development. It highlights the importance of understanding the complex interplay between prenatal stress, opioid systems, and immune system function, paving the way for innovative strategies to protect offspring from the long-term consequences of prenatal stress.
Date :
- Date Completed 2006-01-04
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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